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Cross-Dressing of Multiple Myeloma Cells Mediated by Extracellular Vesicles Conveying MIC and ULBP Ligands Promotes NK Cell Killing

Natural Killer (NK) cells are innate cytotoxic lymphoid cells that play a crucial role in cancer immunosurveillance. NKG2D is an activating receptor that binds to MIC and ULBP molecules typically induced on damaged, transformed, or infected cells. The secretion of NKG2D ligands (NKG2DLs) through pro...

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Detalles Bibliográficos
Autores principales: Vulpis, Elisabetta, Loconte, Luisa, Cassone, Chiara, Antonangeli, Fabrizio, Caracciolo, Giulio, Masuelli, Laura, Fazio, Francesca, Petrucci, Maria Teresa, Fionda, Cinzia, Soriani, Alessandra, Cerboni, Cristina, Cippitelli, Marco, Santoni, Angela, Zingoni, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253317/
https://www.ncbi.nlm.nih.gov/pubmed/37298418
http://dx.doi.org/10.3390/ijms24119467