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Acceptors and Effectors Alter Substrate Inhibition Kinetics of a Plant Glucosyltransferase NbUGT72AY1 and Its Mutants

One of the main obstacles in biocatalysis is the substrate inhibition (SI) of enzymes that play important roles in biosynthesis and metabolic regulation in organisms. The promiscuous glycosyltransferase UGT72AY1 from Nicotiana benthamiana is strongly substrate-inhibited by hydroxycoumarins (inhibito...

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Detalles Bibliográficos
Autores principales:	Liao, Jieren, Lederer, Veronika, Bardhi, Alba, Zou, Zhiwei, Hoffmann, Timothy D., Sun, Guangxin, Song, Chuankui, Hoffmann, Thomas, Schwab, Wilfried
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253357/ https://www.ncbi.nlm.nih.gov/pubmed/37298492 http://dx.doi.org/10.3390/ijms24119542

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