Resistance to Resveratrol Treatment in Experimental PTSD Is Associated with Abnormalities in Hepatic Metabolism of Glucocorticoids

Glucocorticoids are metabolized by the CYP3A isoform of cytochrome P450 and by 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1). Experimental data suggest that post-traumatic stress disorder (PTSD) is associated with an increase in hepatic 11β-HSD-1 activity and a concomitant decrease in hepatic...

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Detalles Bibliográficos
Autores principales: Tseilikman, Vadim E., Fedotova, Julia O., Tseilikman, Olga B., Novak, Jurica, Karpenko, Marina N., Maistrenko, Victoria A., Lazuko, Svetlana S., Belyeva, Lyudmila E., Kamel, Mustapha, Buhler, Alexey V., Kovaleva, Elena G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253377/
https://www.ncbi.nlm.nih.gov/pubmed/37298287
http://dx.doi.org/10.3390/ijms24119333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253377/
https://www.ncbi.nlm.nih.gov/pubmed/37298287
http://dx.doi.org/10.3390/ijms24119333

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