Cargando…

The Curcumin Analog PAC Is a Potential Solution for the Treatment of Triple-Negative Breast Cancer by Modulating the Gene Expression of DNA Repair Pathways

Breast Cancer (BC) is one of the most common and challenging cancers among females worldwide. Conventional treatments for oral cancer rely on the use of radiology and surgery accompanied by chemotherapy. Chemotherapy presents many side effects, and the cells often develop resistance to this chemothe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Almalki, Esraa, Al-Amri, Abdullah, Alrashed, Reem, AL-Zharani, Mohamed, Semlali, Abdelhabib
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253416/ https://www.ncbi.nlm.nih.gov/pubmed/37298600 http://dx.doi.org/10.3390/ijms24119649

Ejemplares similares

Synergistic Effects of New Curcumin Analog (PAC) and Cisplatin on Oral Cancer Therapy
por: Semlali, Abdelhabib, et al.
Publicado: (2023)

The curcumin analog (PAC) suppressed cell survival and induced apoptosis and autophagy in oral cancer cells
por: Semlali, Abdelhabib, et al.
Publicado: (2021)

Oxidative Stress and Autophagy Mediate Anti-Cancer Properties of Cannabis Derivatives in Human Oral Cancer Cells
por: Loubaki, Lionel, et al.
Publicado: (2022)

Cannabinoid Mixture Affects the Fate and Functions of B Cells through the Modulation of the Caspase and MAP Kinase Pathways
por: Lampron, Marie-Claude, et al.
Publicado: (2023)

Synergistic Effect of Anethole and Platinum Drug Cisplatin against Oral Cancer Cell Growth and Migration by Inhibiting MAPKase, Beta-Catenin, and NF-κB Pathways
por: Semlali, Abdelhabib, et al.
Publicado: (2023)

Toll-like receptor 4 as a predictor of clinical outcomes of estrogen receptor-negative breast cancer in Saudi women
por: Semlali, Abdelhabib, et al.
Publicado: (2017)

Two SNPs in the promoter region of Toll-like receptor 4 gene are not associated with smoking in Saudi Arabia
por: Kohailan, Muhammad, et al.
Publicado: (2017)

Expression and allele frequencies of Thymic stromal lymphopoietin are a key factor of breast cancer risk
por: Semlali, Abdelhabib, et al.
Publicado: (2019)

Sarcocystis camelicanis increases interleukin (IL)-6 expression in one-humped camels (Camelus dromedarius) from Riyadh and Al Qassim, Saudi Arabia
por: Metwally, Dina M., et al.
Publicado: (2021)

Effects of Hexane Root Extract of Ferula hermonis Boiss. on Human Breast and Colon Cancer Cells: An In Vitro and In Vivo Study
por: Abutaha, Nael, et al.
Publicado: (2019)

The curcumin analogue PAC has potent anti-anaplastic thyroid cancer effects
por: Al-Mohanna, Mai, et al.
Publicado: (2023)

Novel sequence variants in the TLR6 gene associated with advanced breast cancer risk in the Saudi Arabian population
por: Semlali, Abdelhabib, et al.
Publicado: (2018)

No genetic relationship between TLR2 rs4696480, rs3804100, and rs3804099 gene polymorphisms and female breast cancer in Saudi populations
por: Semlali, Abdelhabib, et al.
Publicado: (2017)

TSLP and TSLP receptors variants are associated with smoking
por: Semlali, Abdelhabib, et al.
Publicado: (2019)

Mevacor/Poly(vinyl acetate/2-hydroxyethyl methacrylate) as Solid Solution: Preparation, Solubility Enhancement and Drug Delivery
por: Alassaf, Mohammed, et al.
Publicado: (2023)

No associations between aromatase gene polymorphisms and breast cancer risk in Saudi patients
por: Alanazi, Mohammed, et al.
Publicado: (2015)

A Significant Increasing Risk Association between Cigarette Smoking and XPA and XPC Genes Polymorphisms
por: Almushawwah, Safiah, et al.
Publicado: (2023)

Data on the alizarin red S adsorption from aqueous solutions on PAC, treated PAC, and PAC/γ≈Fe(2)O(3)
por: Kamarehie, Bahram, et al.
Publicado: (2018)

Data on the bisphenol A adsorption from aqueous solutions on PAC and MgO~PAC crystals
por: Kamarehie, Bahram, et al.
Publicado: (2018)

C. albicans growth, transition, biofilm formation, and gene expression modulation by antimicrobial decapeptide KSL-W
por: Theberge, Simon, et al.
Publicado: (2013)

Toll‐like receptor 4 polymorphisms in Saudi population with cardiovascular diseases
por: Semlali, Abdelhabib, et al.
Publicado: (2019)

Curcumin–Copper Complex Nanoparticles for the Management of Triple-Negative Breast Cancer
por: Greish, Khaled, et al.
Publicado: (2018)

Expression and New Exon Mutations of the Human Beta Defensins and Their Association on Colon Cancer Development
por: Semlali, Abdelhabib, et al.
Publicado: (2015)

Potential role of Toll-like receptor 2 expression and polymorphisms in colon cancer susceptibility in the Saudi Arabian population
por: Semlali, Abdelhabib, et al.
Publicado: (2018)

Whole Cigarette Smoke Increased the Expression of TLRs, HBDs, and Proinflammory Cytokines by Human Gingival Epithelial Cells through Different Signaling Pathways
por: Semlali, Abdelhabib, et al.
Publicado: (2012)

E-Cigarettes Increase Candida albicans Growth and Modulate its Interaction with Gingival Epithelial Cells
por: Alanazi, Humidah, et al.
Publicado: (2019)

Editorial: Targeting redox regulation and autophagy systems for cancer therapy
por: Zhang, Junmin, et al.
Publicado: (2023)

Antischistosomal and anti-inflammatory activity of garlic and allicin compared with that of praziquantel in vivo
por: Metwally, Dina M., et al.
Publicado: (2018)

PAC in FACTT: Time to PAC it in?
por: Mansour, Wissam, et al.
Publicado: (2008)

Effect of the thymine‐DNA glycosylase rs4135050 variant on Saudi smoker population
por: Almutairi, Mikhlid, et al.
Publicado: (2019)

Inhibition of HIV-1 by curcumin A, a novel curcumin analog
por: Kumari, Namita, et al.
Publicado: (2015)

Effect of smoking on the genetic makeup of toll-like receptors 2 and 6
por: Kohailan, Muhammad, et al.
Publicado: (2016)

Curcumin restores sensitivity to retinoic acid in triple negative breast cancer cells
por: Thulasiraman, Padmamalini, et al.
Publicado: (2014)

Development of Stable Amino-Pyrimidine–Curcumin Analogs: Synthesis, Equilibria in Solution, and Potential Anti-Proliferative Activity
por: Mari, Matteo, et al.
Publicado: (2023)

Iodide Analogs of Arsenoplatins—Potential Drug Candidates for Triple Negative Breast Cancers
por: Miodragović, Ðenana, et al.
Publicado: (2021)

GC-MS profiling and assessment of antioxidant, antibacterial, and anticancer properties of extracts of Annona squamosa L. leaves
por: Al-Nemari, Rawan, et al.
Publicado: (2020)

Naproxen-Loaded Poly(2-hydroxyalkyl methacrylates): Preparation and Drug Release Dynamics
por: Aljubailah, Abeer, et al.
Publicado: (2022)

Cigarette smoke condensate increases C. albicans adhesion, growth, biofilm formation, and EAP1, HWP1 and SAP2 gene expression
por: Semlali, Abdelhabib, et al.
Publicado: (2014)

Anethole induces anti-oral cancer activity by triggering apoptosis, autophagy and oxidative stress and by modulation of multiple signaling pathways
por: Contant, Camille, et al.
Publicado: (2021)

Rapamycin inhibits oral cancer cell growth by promoting oxidative stress and suppressing ERK1/2, NF-κB and beta-catenin pathways
por: Semlali, Abdelhabib, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j7dolhftopsj296crmdrb04o2d