FOXO3 Deficiency in Neutrophils Drives Colonic Inflammation and Tumorigenesis

Inflammatory bowel disease (IBD), characterized by infiltration of polymorphonuclear neutrophils (PMNs), increases the risk of colon cancer. PMN activation corresponds to the accumulation of intracellular Lipid Droplets (LDs). As increased LDs are negatively regulated by transcription factor Forkhea...

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Detalles Bibliográficos
Autores principales: Ghimire, Jenisha, Iftikhar, Rida, Penrose, Harrison M., Snarski, Patricia, Ruiz, Emmanuelle, Savkovic, Suzana D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253470/
https://www.ncbi.nlm.nih.gov/pubmed/37298680
http://dx.doi.org/10.3390/ijms24119730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253470/
https://www.ncbi.nlm.nih.gov/pubmed/37298680
http://dx.doi.org/10.3390/ijms24119730

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