Cargando…

Laser-Induced Fabrication of Micro-Optics on Bioresorbable Calcium Phosphate Glass for Implantable Devices

In this study, a single-step nanosecond laser-induced generation of micro-optical features is demonstrated on an antibacterial bioresorbable Cu-doped calcium phosphate glass. The inverse Marangoni flow of the laser-generated melt is exploited for the fabrication of microlens arrays and diffraction g...

Descripción completa

Detalles Bibliográficos
Autores principales: Meena Narayana Menon, Devanarayanan, Pugliese, Diego, Giardino, Matteo, Janner, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253483/
https://www.ncbi.nlm.nih.gov/pubmed/37297033
http://dx.doi.org/10.3390/ma16113899
_version_ 1785056416655998976
author Meena Narayana Menon, Devanarayanan
Pugliese, Diego
Giardino, Matteo
Janner, Davide
author_facet Meena Narayana Menon, Devanarayanan
Pugliese, Diego
Giardino, Matteo
Janner, Davide
author_sort Meena Narayana Menon, Devanarayanan
collection PubMed
description In this study, a single-step nanosecond laser-induced generation of micro-optical features is demonstrated on an antibacterial bioresorbable Cu-doped calcium phosphate glass. The inverse Marangoni flow of the laser-generated melt is exploited for the fabrication of microlens arrays and diffraction gratings. The process is realized in a matter of few seconds and, by optimizing the laser parameters, micro-optical features with a smooth surface are obtained showing a good optical quality. The tunability of the microlens’ dimensions is achieved by varying the laser power, allowing the obtaining of multi-focal microlenses that are of great interest for three-dimensional (3D) imaging. Furthermore, the microlens’ shape can be tuned between hyperboloid and spherical. The fabricated microlenses exhibited good focusing and imaging performance and the variable focal lengths were measured experimentally, showing good agreement with the calculated values. The diffraction gratings obtained by this method showed the typical periodic pattern with a first-order efficiency of about 5.1%. Finally, the dissolution characteristics of the fabricated micropatterns were studied in a phosphate-buffered saline solution (PBS, pH = 7.4) demonstrating the bioresorbability of the micro-optical components. This study offers a new approach for the fabrication of micro-optics on bioresorbable glass, which could enable the manufacturing of new implantable optical sensing components for biomedical applications.
format Online
Article
Text
id pubmed-10253483
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-102534832023-06-10 Laser-Induced Fabrication of Micro-Optics on Bioresorbable Calcium Phosphate Glass for Implantable Devices Meena Narayana Menon, Devanarayanan Pugliese, Diego Giardino, Matteo Janner, Davide Materials (Basel) Article In this study, a single-step nanosecond laser-induced generation of micro-optical features is demonstrated on an antibacterial bioresorbable Cu-doped calcium phosphate glass. The inverse Marangoni flow of the laser-generated melt is exploited for the fabrication of microlens arrays and diffraction gratings. The process is realized in a matter of few seconds and, by optimizing the laser parameters, micro-optical features with a smooth surface are obtained showing a good optical quality. The tunability of the microlens’ dimensions is achieved by varying the laser power, allowing the obtaining of multi-focal microlenses that are of great interest for three-dimensional (3D) imaging. Furthermore, the microlens’ shape can be tuned between hyperboloid and spherical. The fabricated microlenses exhibited good focusing and imaging performance and the variable focal lengths were measured experimentally, showing good agreement with the calculated values. The diffraction gratings obtained by this method showed the typical periodic pattern with a first-order efficiency of about 5.1%. Finally, the dissolution characteristics of the fabricated micropatterns were studied in a phosphate-buffered saline solution (PBS, pH = 7.4) demonstrating the bioresorbability of the micro-optical components. This study offers a new approach for the fabrication of micro-optics on bioresorbable glass, which could enable the manufacturing of new implantable optical sensing components for biomedical applications. MDPI 2023-05-23 /pmc/articles/PMC10253483/ /pubmed/37297033 http://dx.doi.org/10.3390/ma16113899 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Meena Narayana Menon, Devanarayanan
Pugliese, Diego
Giardino, Matteo
Janner, Davide
Laser-Induced Fabrication of Micro-Optics on Bioresorbable Calcium Phosphate Glass for Implantable Devices
title Laser-Induced Fabrication of Micro-Optics on Bioresorbable Calcium Phosphate Glass for Implantable Devices
title_full Laser-Induced Fabrication of Micro-Optics on Bioresorbable Calcium Phosphate Glass for Implantable Devices
title_fullStr Laser-Induced Fabrication of Micro-Optics on Bioresorbable Calcium Phosphate Glass for Implantable Devices
title_full_unstemmed Laser-Induced Fabrication of Micro-Optics on Bioresorbable Calcium Phosphate Glass for Implantable Devices
title_short Laser-Induced Fabrication of Micro-Optics on Bioresorbable Calcium Phosphate Glass for Implantable Devices
title_sort laser-induced fabrication of micro-optics on bioresorbable calcium phosphate glass for implantable devices
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253483/
https://www.ncbi.nlm.nih.gov/pubmed/37297033
http://dx.doi.org/10.3390/ma16113899
work_keys_str_mv AT meenanarayanamenondevanarayanan laserinducedfabricationofmicroopticsonbioresorbablecalciumphosphateglassforimplantabledevices
AT pugliesediego laserinducedfabricationofmicroopticsonbioresorbablecalciumphosphateglassforimplantabledevices
AT giardinomatteo laserinducedfabricationofmicroopticsonbioresorbablecalciumphosphateglassforimplantabledevices
AT jannerdavide laserinducedfabricationofmicroopticsonbioresorbablecalciumphosphateglassforimplantabledevices