Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation

Chemoresistance blunts the efficacy of temozolomide (TMZ) in the treatment of glioblastoma (GBM). Elevated levels of O6-methylguanine-DNA methyltransferase (MGMT) and activation of signal transducer and of transcription 3 (STAT3) have been reported to correlate with GBM resistance to alkylator chemo...

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Detalles Bibliográficos
Autores principales: Wu, Moli, Song, Danyang, Li, Hui, Ahmad, Nisar, Xu, Hong, Yang, Xiaobo, Wang, Qian, Cheng, Xiaoxin, Deng, Sa, Shu, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253519/
https://www.ncbi.nlm.nih.gov/pubmed/37298405
http://dx.doi.org/10.3390/ijms24119453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253519/
https://www.ncbi.nlm.nih.gov/pubmed/37298405
http://dx.doi.org/10.3390/ijms24119453

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