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Resveratrol Enhances Temozolomide Efficacy in Glioblastoma Cells through Downregulated MGMT and Negative Regulators-Related STAT3 Inactivation

Chemoresistance blunts the efficacy of temozolomide (TMZ) in the treatment of glioblastoma (GBM). Elevated levels of O6-methylguanine-DNA methyltransferase (MGMT) and activation of signal transducer and of transcription 3 (STAT3) have been reported to correlate with GBM resistance to alkylator chemo...

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Detalles Bibliográficos
Autores principales:	Wu, Moli, Song, Danyang, Li, Hui, Ahmad, Nisar, Xu, Hong, Yang, Xiaobo, Wang, Qian, Cheng, Xiaoxin, Deng, Sa, Shu, Xiaohong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253519/ https://www.ncbi.nlm.nih.gov/pubmed/37298405 http://dx.doi.org/10.3390/ijms24119453

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