MDM2 Implications for Potential Molecular Pathogenic Therapies of Soft-Tissue Tumors

Murine double minute 2 (MDM2, gene name MDM2) is an oncogene that mainly codes for a protein that acts as an E3 ubiquitin ligase, which targets the tumor suppressor protein p53 for degradation. Overexpression of MDM2 regulates the p53 protein levels by binding to it and promoting its degradation by...

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Detalles Bibliográficos
Autores principales: Sun, Sylvia Yao, Crago, Aimee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253559/
https://www.ncbi.nlm.nih.gov/pubmed/37297833
http://dx.doi.org/10.3390/jcm12113638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253559/
https://www.ncbi.nlm.nih.gov/pubmed/37297833
http://dx.doi.org/10.3390/jcm12113638

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