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MDM2 Implications for Potential Molecular Pathogenic Therapies of Soft-Tissue Tumors
Murine double minute 2 (MDM2, gene name MDM2) is an oncogene that mainly codes for a protein that acts as an E3 ubiquitin ligase, which targets the tumor suppressor protein p53 for degradation. Overexpression of MDM2 regulates the p53 protein levels by binding to it and promoting its degradation by...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253559/ https://www.ncbi.nlm.nih.gov/pubmed/37297833 http://dx.doi.org/10.3390/jcm12113638 |