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State of the Art of Genomic Technology in Toxicology: A Review

The rapid growth of genomics techniques has revolutionized and impacted, greatly and positively, the knowledge of toxicology, ushering it into a “new era”: the era of genomic technology (GT). This great advance permits us to analyze the whole genome, to know the gene response to toxicants and enviro...

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Autores principales: Recio-Vega, Rogelio, Facio-Campos, Rolando Adair, Hernández-González, Sandra Isabel, Olivas-Calderón, Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253724/
https://www.ncbi.nlm.nih.gov/pubmed/37298568
http://dx.doi.org/10.3390/ijms24119618
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author Recio-Vega, Rogelio
Facio-Campos, Rolando Adair
Hernández-González, Sandra Isabel
Olivas-Calderón, Edgar
author_facet Recio-Vega, Rogelio
Facio-Campos, Rolando Adair
Hernández-González, Sandra Isabel
Olivas-Calderón, Edgar
author_sort Recio-Vega, Rogelio
collection PubMed
description The rapid growth of genomics techniques has revolutionized and impacted, greatly and positively, the knowledge of toxicology, ushering it into a “new era”: the era of genomic technology (GT). This great advance permits us to analyze the whole genome, to know the gene response to toxicants and environmental stressors, and to determine the specific profiles of gene expression, among many other approaches. The aim of this work was to compile and narrate the recent research on GT during the last 2 years (2020–2022). A literature search was managed using the PubMed and Medscape interfaces on the Medline database. Relevant articles published in peer-reviewed journals were retrieved and their main results and conclusions are mentioned briefly. It is quite important to form a multidisciplinary taskforce on GT with the aim of designing and implementing a comprehensive, collaborative, and a strategic work plan, prioritizing and assessing the most relevant diseases, so as to decrease human morbimortality due to exposure to environmental chemicals and stressors.
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spelling pubmed-102537242023-06-10 State of the Art of Genomic Technology in Toxicology: A Review Recio-Vega, Rogelio Facio-Campos, Rolando Adair Hernández-González, Sandra Isabel Olivas-Calderón, Edgar Int J Mol Sci Review The rapid growth of genomics techniques has revolutionized and impacted, greatly and positively, the knowledge of toxicology, ushering it into a “new era”: the era of genomic technology (GT). This great advance permits us to analyze the whole genome, to know the gene response to toxicants and environmental stressors, and to determine the specific profiles of gene expression, among many other approaches. The aim of this work was to compile and narrate the recent research on GT during the last 2 years (2020–2022). A literature search was managed using the PubMed and Medscape interfaces on the Medline database. Relevant articles published in peer-reviewed journals were retrieved and their main results and conclusions are mentioned briefly. It is quite important to form a multidisciplinary taskforce on GT with the aim of designing and implementing a comprehensive, collaborative, and a strategic work plan, prioritizing and assessing the most relevant diseases, so as to decrease human morbimortality due to exposure to environmental chemicals and stressors. MDPI 2023-06-01 /pmc/articles/PMC10253724/ /pubmed/37298568 http://dx.doi.org/10.3390/ijms24119618 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Recio-Vega, Rogelio
Facio-Campos, Rolando Adair
Hernández-González, Sandra Isabel
Olivas-Calderón, Edgar
State of the Art of Genomic Technology in Toxicology: A Review
title State of the Art of Genomic Technology in Toxicology: A Review
title_full State of the Art of Genomic Technology in Toxicology: A Review
title_fullStr State of the Art of Genomic Technology in Toxicology: A Review
title_full_unstemmed State of the Art of Genomic Technology in Toxicology: A Review
title_short State of the Art of Genomic Technology in Toxicology: A Review
title_sort state of the art of genomic technology in toxicology: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253724/
https://www.ncbi.nlm.nih.gov/pubmed/37298568
http://dx.doi.org/10.3390/ijms24119618
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