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Identification of Driver Epistatic Gene Pairs Combining Germline and Somatic Mutations in Cancer
Cancer arises from the complex interplay of various factors. Traditionally, the identification of driver genes focuses primarily on the analysis of somatic mutations. We describe a new method for the detection of driver gene pairs based on an epistasis analysis that considers both germline and somat...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253732/ https://www.ncbi.nlm.nih.gov/pubmed/37298272 http://dx.doi.org/10.3390/ijms24119323 |