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Identification of Driver Epistatic Gene Pairs Combining Germline and Somatic Mutations in Cancer

Cancer arises from the complex interplay of various factors. Traditionally, the identification of driver genes focuses primarily on the analysis of somatic mutations. We describe a new method for the detection of driver gene pairs based on an epistasis analysis that considers both germline and somat...

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Detalles Bibliográficos
Autores principales:	Rocha, Jairo, Sastre, Jaume, Amengual-Cladera, Emilia, Hernandez-Rodriguez, Jessica, Asensio-Landa, Victor, Heine-Suñer, Damià, Capriotti, Emidio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253732/ https://www.ncbi.nlm.nih.gov/pubmed/37298272 http://dx.doi.org/10.3390/ijms24119323

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