Cargando…

Identification of a New RNA and Protein Integrated Biomarker Panel Associated with Kidney Function Impairment in DKD: Translational Implications

Diabetic kidney disease (DKD) is a complication that strongly increases the risk of end-stage kidney disease and cardiovascular events. The identification of novel, highly sensitive, and specific early biomarkers to identify DKD patients and predict kidney function decline is a pivotal aim of transl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scamporrino, Alessandra, Di Mauro, Stefania, Filippello, Agnese, Di Marco, Grazia, Di Pino, Antonino, Scicali, Roberto, Di Marco, Maurizio, Martorana, Emanuele, Malaguarnera, Roberta, Purrello, Francesco, Piro, Salvatore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253864/ https://www.ncbi.nlm.nih.gov/pubmed/37298364 http://dx.doi.org/10.3390/ijms24119412

Ejemplares similares

Update on Diabetic Kidney Disease (DKD): Focus on Non-Albuminuric DKD and Cardiovascular Risk
por: Scilletta, Sabrina, et al.
Publicado: (2023)

Direct Effects of D-Chiro-Inositol on Insulin Signaling and Glucagon Secretion of Pancreatic Alpha Cells
por: Filippello, Agnese, et al.
Publicado: (2020)

Clinical and Molecular Biomarkers for Diagnosis and Staging of NAFLD
por: Di Mauro, Stefania, et al.
Publicado: (2021)

Molecular Effects of Chronic Exposure to Palmitate in Intestinal Organoids: A New Model to Study Obesity and Diabetes
por: Filippello, Agnese, et al.
Publicado: (2022)

Mitochondrial RNAs as Potential Biomarkers of Functional Impairment in Diabetic Kidney Disease
por: Di Mauro, Stefania, et al.
Publicado: (2022)

High Glucose Exposure Impairs L-Cell Differentiation in Intestinal Organoids: Molecular Mechanisms and Clinical Implications
por: Filippello, Agnese, et al.
Publicado: (2021)

Metformin: When Should We Fear Lactic Acidosis?
por: Di Mauro, Stefania, et al.
Publicado: (2022)

Direct and Indirect Effects of SARS-CoV-2 Pandemic in Subjects with Familial Hypercholesterolemia: A Single Lipid-Center Real-World Evaluation
por: Scicali, Roberto, et al.
Publicado: (2021)

Chronic Exposure to Palmitate Impairs Insulin Signaling in an Intestinal L-cell Line: A Possible Shift from GLP-1 to Glucagon Production
por: Filippello, Agnese, et al.
Publicado: (2018)

1 h Postload Glycemia Is Associated with Low Endogenous Secretory Receptor for Advanced Glycation End Product Levels and Early Markers of Cardiovascular Disease
por: Di Pino, Antonino, et al.
Publicado: (2019)

Impaired glucagon suppression and reduced insulin sensitivity in subjects with prediabetes undergoing atorvastatin therapy
por: Urbano, Francesca, et al.
Publicado: (2019)

Analysis of HDL-microRNA panel in heterozygous familial hypercholesterolemia subjects with LDL receptor null or defective mutation
por: Scicali, Roberto, et al.
Publicado: (2019)

Increased Platelet Reactivity and Proinflammatory Profile Are Associated with Intima–Media Thickness and Arterial Stiffness in Prediabetes
por: Di Marco, Maurizio, et al.
Publicado: (2022)

Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress
por: Urbano, Francesca, et al.
Publicado: (2017)

Author Correction: Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress
por: Urbano, Francesca, et al.
Publicado: (2020)

Circulating Coding and Long Non-Coding RNAs as Potential Biomarkers of Idiopathic Pulmonary Fibrosis
por: Di Mauro, Stefania, et al.
Publicado: (2020)

Glucagon as a Therapeutic Approach to Severe Hypoglycemia: After 100 Years, Is It Still the Antidote of Insulin?
por: Porcellati, Francesca, et al.
Publicado: (2021)

An Uncharacterised lncRNA Coded by the ASAP1 Locus Is Downregulated in Serum of Type 2 Diabetes Mellitus Patients
por: Barbagallo, Cristina, et al.
Publicado: (2023)

Serum coding and non‐coding RNAs as biomarkers of NAFLD and fibrosis severity
por: Di Mauro, Stefania, et al.
Publicado: (2019)

Coffee Restores Expression of lncRNAs Involved in Steatosis and Fibrosis in a Mouse Model of NAFLD
por: Di Mauro, Stefania, et al.
Publicado: (2021)

May statins and PCSK9 inhibitors be protective from COVID-19 in familial hypercholesterolemia subjects?
por: Scicali, Roberto, et al.
Publicado: (2020)

Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department
por: Miano, Nicoletta, et al.
Publicado: (2023)

Analysis of Arterial Stiffness and Sexual Function after Adding on PCSK9 Inhibitor Treatment in Male Patients with Familial Hypercholesterolemia: A Single Lipid Center Real-World Experience
por: Scicali, Roberto, et al.
Publicado: (2020)

Effect of PCSK9 inhibitors on pulse wave velocity and monocyte-to-HDL-cholesterol ratio in familial hypercholesterolemia subjects: results from a single-lipid-unit real-life setting
por: Scicali, Roberto, et al.
Publicado: (2021)

Management of Statin Intolerant Patients in the Era of Novel Lipid Lowering Therapies: A Critical Approach in Clinical Practice
por: Bosco, Giosiana, et al.
Publicado: (2023)

Chronic Exposure to GLP-1 Increases GLP-1 Synthesis and Release in a Pancreatic Alpha Cell Line (α-TC1): Evidence of a Direct Effect of GLP-1 on Pancreatic Alpha Cells
por: Piro, Salvatore, et al.
Publicado: (2014)

Pathophysiological, Molecular and Therapeutic Issues of Nonalcoholic Fatty Liver Disease: An Overview
por: Marchisello, Simona, et al.
Publicado: (2019)

Direct and indirect effects of SARS-CoV-2 pandemic in subjects with familial hypercholesterolemia: A single lipid-center real-world evaluation
por: Scicali, R., et al.
Publicado: (2022)

Is COVID-19 All That Glitters?
por: Spampinato, Salvatore, et al.
Publicado: (2023)

Indirect Effects of the COVID-19 Pandemic on In-Hospital Outcomes among Internal Medicine Departments: A Double-Center Retrospective Study
por: Di Marco, Maurizio, et al.
Publicado: (2023)

Update on pre-diabetes: Focus on diagnostic criteria and cardiovascular risk
por: Di Pino, Antonino, et al.
Publicado: (2016)

Effects of Lipid Lowering Therapy Optimization by PCSK9 Inhibitors on Circulating CD34+ Cells and Pulse Wave Velocity in Familial Hypercholesterolemia Subjects without Atherosclerotic Cardiovascular Disease: Real-World Data from Two Lipid Units
por: Scicali, Roberto, et al.
Publicado: (2022)

Effects of PCSK9 inhibitors on HDL cholesterol efflux and serum cholesterol loading capacity in familial hypercholesterolemia subjects: a multi-lipid-center real-world evaluation
por: Palumbo, Marcella, et al.
Publicado: (2022)

PCSK9 Plasma Levels Are Associated with Mechanical Vascular Impairment in Familial Hypercholesterolemia Subjects without a History of Atherosclerotic Cardiovascular Disease: Results of Six-Month Add-On PCSK9 Inhibitor Therapy
por: Toscano, Arianna, et al.
Publicado: (2022)

Thyroid Cancer and Circadian Clock Disruption
por: Malaguarnera, Roberta, et al.
Publicado: (2020)

Generalizability of FIGARO‐DKD and FIDELIO‐DKD Trial Criteria to the US Population Eligible for Finerenone
por: Chiu, Nicholas, et al.
Publicado: (2022)

Network Pharmacology-Based Prediction of Mechanism of Shenzhuo Formula for Application to DKD
por: Wang, Xinmiao, et al.
Publicado: (2021)

Editorial on the Special Issue: “Pancreatic Islets of Langerhans: Not Only Beta-Cells”
por: Malaguarnera, Roberta, et al.
Publicado: (2021)

Detection of DKD stage 1 and treatment are essential
por: Futrakul, Narisa, et al.
Publicado: (2018)

Finerenone in Black Patients With Type 2 Diabetes and CKD: A Post hoc Analysis of the Pooled FIDELIO-DKD and FIGARO-DKD Trials
por: Flack, John M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_gn4pijvoflve70ul12lekuk8qn