Pharmacological Analysis of GABA(A) Receptor and Sigma1R Chaperone Interaction: Research Report I―Investigation of the Anxiolytic, Anticonvulsant and Hypnotic Effects of Allosteric GABA(A) Receptors’ Ligands

Two groups of facts have been established in previous drug development studies of the non-benzodiazepine anxiolytic fabomotizole. First, fabomotizole prevents stress-induced decrease in binding ability of the GABA(A) receptor’s benzodiazepine site. Second, fabomotizole is a Sigma1R chaperone agonist...

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Detalles Bibliográficos
Autores principales: Voronin, Mikhail V., Shangin, Stanislav V., Litvinova, Svetlana A., Abramova, Elena V., Kurbanov, Rustam D., Rybina, Inna V., Vakhitova, Yulia V., Seredenin, Sergei B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10253922/
https://www.ncbi.nlm.nih.gov/pubmed/37298532
http://dx.doi.org/10.3390/ijms24119580

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