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Identification of key mutations responsible for the enhancement of receptor-binding affinity and immune escape of SARS-CoV-2 Omicron variant

The Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has raised concerns worldwide due to its enhanced transmissibility and immune escapability. The first dominant Omicron BA.1 subvariant harbors more than 30 mutations in the spike protein from the prototype virus, of...

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Detalles Bibliográficos
Autores principales: Wang, Wei Bu, Ma, Yi Bo, Lei, Ze Hua, Zhang, Xue Feng, Li, Jiao, Li, Shan Shan, Dong, Ze Yuan, Liang, Yu, Li, Qi Ming, Su, Ji Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254043/
https://www.ncbi.nlm.nih.gov/pubmed/37352723
http://dx.doi.org/10.1016/j.jmgm.2023.108540