The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice

Oral cancer is primarily squamous-cell carcinoma with a 5-year survival rate of approximately 50%. Lysyl oxidase (LOX) participates in collagen and elastin maturation. The propeptide of LOX is released as an 18 kDa protein (LOX-PP) in the extracellular environment by procollagen C-proteinases and ha...

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Detalles Bibliográficos
Autores principales: Peymanfar, Yaser, Mahjour, Faranak, Shrestha, Neha, de la Cueva, Ana, Chen, Ying, Huang, Shengyuan, Kirsch, Kathrin H., Han, Xiaozhe, Trackman, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254048/
https://www.ncbi.nlm.nih.gov/pubmed/37298359
http://dx.doi.org/10.3390/ijms24119407