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The Lysyl Oxidase G473A Polymorphism Exacerbates Oral Cancer Development in Humans and Mice
Oral cancer is primarily squamous-cell carcinoma with a 5-year survival rate of approximately 50%. Lysyl oxidase (LOX) participates in collagen and elastin maturation. The propeptide of LOX is released as an 18 kDa protein (LOX-PP) in the extracellular environment by procollagen C-proteinases and ha...
Autores principales: | Peymanfar, Yaser, Mahjour, Faranak, Shrestha, Neha, de la Cueva, Ana, Chen, Ying, Huang, Shengyuan, Kirsch, Kathrin H., Han, Xiaozhe, Trackman, Philip C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254048/ https://www.ncbi.nlm.nih.gov/pubmed/37298359 http://dx.doi.org/10.3390/ijms24119407 |
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