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Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants
In our research, our goal was to develop a characterization method that can be universally applied to periodic cell structures. Our work involved the accurate tuning of the stiffness properties of cellular structure components that can significantly reduce the number of revision surgeries. Up to dat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254473/ https://www.ncbi.nlm.nih.gov/pubmed/37297280 http://dx.doi.org/10.3390/ma16114146 |
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author | Nemes-Károly, István Szebényi, Gábor |
author_facet | Nemes-Károly, István Szebényi, Gábor |
author_sort | Nemes-Károly, István |
collection | PubMed |
description | In our research, our goal was to develop a characterization method that can be universally applied to periodic cell structures. Our work involved the accurate tuning of the stiffness properties of cellular structure components that can significantly reduce the number of revision surgeries. Up to date porous, cellular structures provide the best possible osseointegration, while stress shielding and micromovements at the bone-implant interface can be reduced by implants with elastic properties equivalent to bone tissue. Furthermore, it is possible to store a drug inside implants with a cellular structure, for which we have also prepared a viable model. In the literature, there is currently no established uniform stiffness sizing procedure for periodic cellular structures but also no uniform designation to identify the structures. A uniform marking system for cellular structures was proposed. We developed a multi-step exact stiffness design and validation methodology. The method consists of a combination of FE (Finite Element) simulations and mechanical compression tests with fine strain measurement, which are finally used to accurately set the stiffness of components. We succeeded in reducing the stiffness of test specimens designed by us to a level equivalent to that of bone (7–30 GPa), and all of this was also validated with FE simulation. |
format | Online Article Text |
id | pubmed-10254473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102544732023-06-10 Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants Nemes-Károly, István Szebényi, Gábor Materials (Basel) Article In our research, our goal was to develop a characterization method that can be universally applied to periodic cell structures. Our work involved the accurate tuning of the stiffness properties of cellular structure components that can significantly reduce the number of revision surgeries. Up to date porous, cellular structures provide the best possible osseointegration, while stress shielding and micromovements at the bone-implant interface can be reduced by implants with elastic properties equivalent to bone tissue. Furthermore, it is possible to store a drug inside implants with a cellular structure, for which we have also prepared a viable model. In the literature, there is currently no established uniform stiffness sizing procedure for periodic cellular structures but also no uniform designation to identify the structures. A uniform marking system for cellular structures was proposed. We developed a multi-step exact stiffness design and validation methodology. The method consists of a combination of FE (Finite Element) simulations and mechanical compression tests with fine strain measurement, which are finally used to accurately set the stiffness of components. We succeeded in reducing the stiffness of test specimens designed by us to a level equivalent to that of bone (7–30 GPa), and all of this was also validated with FE simulation. MDPI 2023-06-02 /pmc/articles/PMC10254473/ /pubmed/37297280 http://dx.doi.org/10.3390/ma16114146 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Nemes-Károly, István Szebényi, Gábor Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants |
title | Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants |
title_full | Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants |
title_fullStr | Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants |
title_full_unstemmed | Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants |
title_short | Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants |
title_sort | reliable methods for classification, characterization, and design of cellular structures for patient-specific implants |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254473/ https://www.ncbi.nlm.nih.gov/pubmed/37297280 http://dx.doi.org/10.3390/ma16114146 |
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