Cargando…

Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants

In our research, our goal was to develop a characterization method that can be universally applied to periodic cell structures. Our work involved the accurate tuning of the stiffness properties of cellular structure components that can significantly reduce the number of revision surgeries. Up to dat...

Descripción completa

Detalles Bibliográficos
Autores principales: Nemes-Károly, István, Szebényi, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254473/
https://www.ncbi.nlm.nih.gov/pubmed/37297280
http://dx.doi.org/10.3390/ma16114146
_version_ 1785056652288851968
author Nemes-Károly, István
Szebényi, Gábor
author_facet Nemes-Károly, István
Szebényi, Gábor
author_sort Nemes-Károly, István
collection PubMed
description In our research, our goal was to develop a characterization method that can be universally applied to periodic cell structures. Our work involved the accurate tuning of the stiffness properties of cellular structure components that can significantly reduce the number of revision surgeries. Up to date porous, cellular structures provide the best possible osseointegration, while stress shielding and micromovements at the bone-implant interface can be reduced by implants with elastic properties equivalent to bone tissue. Furthermore, it is possible to store a drug inside implants with a cellular structure, for which we have also prepared a viable model. In the literature, there is currently no established uniform stiffness sizing procedure for periodic cellular structures but also no uniform designation to identify the structures. A uniform marking system for cellular structures was proposed. We developed a multi-step exact stiffness design and validation methodology. The method consists of a combination of FE (Finite Element) simulations and mechanical compression tests with fine strain measurement, which are finally used to accurately set the stiffness of components. We succeeded in reducing the stiffness of test specimens designed by us to a level equivalent to that of bone (7–30 GPa), and all of this was also validated with FE simulation.
format Online
Article
Text
id pubmed-10254473
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-102544732023-06-10 Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants Nemes-Károly, István Szebényi, Gábor Materials (Basel) Article In our research, our goal was to develop a characterization method that can be universally applied to periodic cell structures. Our work involved the accurate tuning of the stiffness properties of cellular structure components that can significantly reduce the number of revision surgeries. Up to date porous, cellular structures provide the best possible osseointegration, while stress shielding and micromovements at the bone-implant interface can be reduced by implants with elastic properties equivalent to bone tissue. Furthermore, it is possible to store a drug inside implants with a cellular structure, for which we have also prepared a viable model. In the literature, there is currently no established uniform stiffness sizing procedure for periodic cellular structures but also no uniform designation to identify the structures. A uniform marking system for cellular structures was proposed. We developed a multi-step exact stiffness design and validation methodology. The method consists of a combination of FE (Finite Element) simulations and mechanical compression tests with fine strain measurement, which are finally used to accurately set the stiffness of components. We succeeded in reducing the stiffness of test specimens designed by us to a level equivalent to that of bone (7–30 GPa), and all of this was also validated with FE simulation. MDPI 2023-06-02 /pmc/articles/PMC10254473/ /pubmed/37297280 http://dx.doi.org/10.3390/ma16114146 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nemes-Károly, István
Szebényi, Gábor
Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants
title Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants
title_full Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants
title_fullStr Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants
title_full_unstemmed Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants
title_short Reliable Methods for Classification, Characterization, and Design of Cellular Structures for Patient-Specific Implants
title_sort reliable methods for classification, characterization, and design of cellular structures for patient-specific implants
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254473/
https://www.ncbi.nlm.nih.gov/pubmed/37297280
http://dx.doi.org/10.3390/ma16114146
work_keys_str_mv AT nemeskarolyistvan reliablemethodsforclassificationcharacterizationanddesignofcellularstructuresforpatientspecificimplants
AT szebenyigabor reliablemethodsforclassificationcharacterizationanddesignofcellularstructuresforpatientspecificimplants