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Phenolic-Rich Extracts from Circular Economy: Chemical Profile and Activity against Filamentous Fungi and Dermatophytes
Fungal infections represent a relevant issue in agri-food and biomedical fields because they could compromise quality of food and humans’ health. Natural extracts represent a safe alternative to synthetic fungicides and in the green chemistry and circular economy scenario, agro-industrial wastes and...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254516/ https://www.ncbi.nlm.nih.gov/pubmed/37298850 http://dx.doi.org/10.3390/molecules28114374 |
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author | Lombardi, Andrea Campo, Margherita Vignolini, Pamela Papalini, Marco Pizzetti, Mirco Bernini, Roberta |
author_facet | Lombardi, Andrea Campo, Margherita Vignolini, Pamela Papalini, Marco Pizzetti, Mirco Bernini, Roberta |
author_sort | Lombardi, Andrea |
collection | PubMed |
description | Fungal infections represent a relevant issue in agri-food and biomedical fields because they could compromise quality of food and humans’ health. Natural extracts represent a safe alternative to synthetic fungicides and in the green chemistry and circular economy scenario, agro-industrial wastes and by-products offer an eco-friendly source of bioactive natural compounds. In this paper, phenolic-rich extracts from Olea europaea L. de-oiled pomace, Castanea sativa Mill. wood, Punica granatum L. peel, and Vitis vinifera L. pomace and seeds were characterized by HPLC-MS-DAD analysis. Finally, these extracts were tested as antimicrobial agents against pathogenic filamentous fungi and dermatophytes such as Aspergillus brasiliensis, Alternaria sp., Rhizopus stolonifer, and Trichophyton interdigitale. The experimental results evidenced that all extracts exhibited a significant growth inhibition for Trichophyton interdigitale. Punica granatum L., Castanea sativa Mill., and Vitis vinifera L. extracts showed a high activity against Alternaria sp. and Rhizopus stolonifer. These data are promising for the potential applications of some of these extracts as antifungal agents in the food and biomedical fields. |
format | Online Article Text |
id | pubmed-10254516 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102545162023-06-10 Phenolic-Rich Extracts from Circular Economy: Chemical Profile and Activity against Filamentous Fungi and Dermatophytes Lombardi, Andrea Campo, Margherita Vignolini, Pamela Papalini, Marco Pizzetti, Mirco Bernini, Roberta Molecules Article Fungal infections represent a relevant issue in agri-food and biomedical fields because they could compromise quality of food and humans’ health. Natural extracts represent a safe alternative to synthetic fungicides and in the green chemistry and circular economy scenario, agro-industrial wastes and by-products offer an eco-friendly source of bioactive natural compounds. In this paper, phenolic-rich extracts from Olea europaea L. de-oiled pomace, Castanea sativa Mill. wood, Punica granatum L. peel, and Vitis vinifera L. pomace and seeds were characterized by HPLC-MS-DAD analysis. Finally, these extracts were tested as antimicrobial agents against pathogenic filamentous fungi and dermatophytes such as Aspergillus brasiliensis, Alternaria sp., Rhizopus stolonifer, and Trichophyton interdigitale. The experimental results evidenced that all extracts exhibited a significant growth inhibition for Trichophyton interdigitale. Punica granatum L., Castanea sativa Mill., and Vitis vinifera L. extracts showed a high activity against Alternaria sp. and Rhizopus stolonifer. These data are promising for the potential applications of some of these extracts as antifungal agents in the food and biomedical fields. MDPI 2023-05-26 /pmc/articles/PMC10254516/ /pubmed/37298850 http://dx.doi.org/10.3390/molecules28114374 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Lombardi, Andrea Campo, Margherita Vignolini, Pamela Papalini, Marco Pizzetti, Mirco Bernini, Roberta Phenolic-Rich Extracts from Circular Economy: Chemical Profile and Activity against Filamentous Fungi and Dermatophytes |
title | Phenolic-Rich Extracts from Circular Economy: Chemical Profile and Activity against Filamentous Fungi and Dermatophytes |
title_full | Phenolic-Rich Extracts from Circular Economy: Chemical Profile and Activity against Filamentous Fungi and Dermatophytes |
title_fullStr | Phenolic-Rich Extracts from Circular Economy: Chemical Profile and Activity against Filamentous Fungi and Dermatophytes |
title_full_unstemmed | Phenolic-Rich Extracts from Circular Economy: Chemical Profile and Activity against Filamentous Fungi and Dermatophytes |
title_short | Phenolic-Rich Extracts from Circular Economy: Chemical Profile and Activity against Filamentous Fungi and Dermatophytes |
title_sort | phenolic-rich extracts from circular economy: chemical profile and activity against filamentous fungi and dermatophytes |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254516/ https://www.ncbi.nlm.nih.gov/pubmed/37298850 http://dx.doi.org/10.3390/molecules28114374 |
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