Cargando…

Exploiting Blood Transport Proteins as Carborane Supramolecular Vehicles for Boron Neutron Capture Therapy

Carboranes are promising agents for applications in boron neutron capture therapy (BNCT), but their hydrophobicity prevents their use in physiological environments. Here, by using reverse docking and molecular dynamics (MD) simulations, we identified blood transport proteins as candidate carriers of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marforio, Tainah Dorina, Mattioli, Edoardo Jun, Zerbetto, Francesco, Calvaresi, Matteo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254601/ https://www.ncbi.nlm.nih.gov/pubmed/37299673 http://dx.doi.org/10.3390/nano13111770

Ejemplares similares

In Vivo Application of Carboranes for Boron Neutron Capture Therapy (BNCT): Structure, Formulation and Analytical Methods for Detection
por: Marforio, Tainah Dorina, et al.
Publicado: (2023)

Dissecting the Supramolecular Dispersion of Fullerenes by Proteins/Peptides: Amino Acid Ranking and Driving Forces for Binding to C(60)
por: Marforio, Tainah Dorina, et al.
Publicado: (2021)

Fullerenes against COVID-19: Repurposing C(60) and C(70) to Clog the Active Site of SARS-CoV-2 Protease
por: Marforio, Tainah Dorina, et al.
Publicado: (2022)

Deciphering the Reactive Pathways of Competitive Reactions inside Carbon Nanotubes
por: Marforio, Tainah Dorina, et al.
Publicado: (2022)

Identification of Blood Transport Proteins to Carry Temoporfin: A Domino Approach from Virtual Screening to Synthesis and In Vitro PDT Testing
por: Marconi, Alessia, et al.
Publicado: (2023)

Electron Dynamics with Explicit-Time Density Functional Theory of the [4+2] Diels–Alder Reaction
por: Acocella, Angela, et al.
Publicado: (2020)

Enhanced Uptake and Phototoxicity of C(60)@albumin Hybrids by Folate Bioconjugation
por: Cantelli, Andrea, et al.
Publicado: (2022)

Dissecting the Interactions between Chlorin e6 and Human Serum Albumin
por: Marconi, Alessia, et al.
Publicado: (2023)

Carrying Temoporfin with Human Serum Albumin: A New Perspective for Photodynamic Application in Head and Neck Cancer
por: Mattioli, Edoardo Jun, et al.
Publicado: (2022)

Light-Enhanced Cytotoxicity of Doxorubicin by Photoactivation
por: Greco, Giulia, et al.
Publicado: (2023)

Identification and Biological Evaluation of a Water-Soluble Fullerene Nanomaterial as BTK Kinase Inhibitor
por: Malarz, Katarzyna, et al.
Publicado: (2023)

Interactions between Endohedral Metallofullerenes and Proteins: The Gd@C(60)–Lysozyme Model
por: Bologna, Fabio, et al.
Publicado: (2018)

Carborane-Containing Hydroxamate MMP Ligands for the Treatment of Tumors Using Boron Neutron Capture Therapy (BNCT): Efficacy without Tumor Cell Entry
por: Flieger, Sebastian, et al.
Publicado: (2023)

Theranostics in Boron Neutron Capture Therapy
por: Sauerwein, Wolfgang A. G., et al.
Publicado: (2021)

Composites and Materials Prepared from Boron Cluster Anions and Carboranes
por: Avdeeva, Varvara V., et al.
Publicado: (2023)

Boron-peptide conjugates with angiopep-2 for boron neutron capture therapy
por: Xiang, Jing, et al.
Publicado: (2023)

Exploiting the Electronic Tuneability of Carboranes as Supports for Frustrated Lewis Pairs
por: Benton, Amanda, et al.
Publicado: (2018)

Conference on Accelerator-based Neutron Sources for Boron Neutron Capture Therapy
Publicado: (1994)

Neutron Tube Design Study for Boron Neutron Capture Therapy Application
por: Verbeke, J M, et al.
Publicado: (1999)

Boron Vehiculating Nanosystems for Neutron Capture Therapy in Cancer Treatment
por: Ailuno, Giorgia, et al.
Publicado: (2022)

Dendritic Structures Functionalized with Boron Clusters, in Particular Carboranes, and Their Biological Properties †
por: Caminade, Anne-Marie, et al.
Publicado: (2023)

Boron microlocalization in oral mucosal tissue: implications for boron neutron capture therapy
por: Morris, G M, et al.
Publicado: (2000)

Nanostructured Boron Nitride With High Water Dispersibility For Boron Neutron Capture Therapy
por: Singh, Bikramjeet, et al.
Publicado: (2016)

Multi-Functional Boron-Delivery Agents for Boron Neutron Capture Therapy of Cancers
por: Oloo, Sebastian O., et al.
Publicado: (2023)

Boron Neutron Capture Therapy for Malignant Brain Tumors
por: MIYATAKE, Shin-Ichi, et al.
Publicado: (2016)

Boron delivery agents for neutron capture therapy of cancer
por: Barth, Rolf F., et al.
Publicado: (2018)

Applicability of Combination with Tirapazamine in Boron Neutron Capture Therapy
por: Masunaga, Shin‐ichiro, et al.
Publicado: (1998)

Boron-neutron Capture on Activated Carbon for Hydrogen Storage
por: Romanos, Jimmy, et al.
Publicado: (2019)

Development of an Imaging Technique for Boron Neutron Capture Therapy
por: Fukumitsu, Nobuyoshi, et al.
Publicado: (2021)

Boron Neutron Capture Therapy: Current Status and Challenges
por: Wang, Song, et al.
Publicado: (2022)

Optimal Neutron Source and Beam Shaping Assembly for Boron Neutron Capture Therapy
por: Vujic, J L, et al.
Publicado: (2003)

Boronophenylalanine, a boron delivery agent for boron neutron capture therapy, is transported by ATB(0,+), LAT1 and LAT2
por: Wongthai, Printip, et al.
Publicado: (2015)

Analysis of boron neutron capture reaction sensitivity using Monte Carlo simulation and proposal of a new dosimetry index in boron neutron capture therapy
por: Takeno, Satoshi, et al.
Publicado: (2022)

Anomeric sugar boronic acid analogues as potential agents for boron neutron capture therapy
por: Imperio, Daniela, et al.
Publicado: (2019)

Boron rich nanotube drug carrier system is suited for boron neutron capture therapy
por: Heide, Fabian, et al.
Publicado: (2021)

A Novel Boron Lipid to Modify Liposomal Surfaces for Boron Neutron Capture Therapy
por: Shirakawa, Makoto, et al.
Publicado: (2021)

An Assessment of the Potential Use of BNNTs for Boron Neutron Capture Therapy
por: Ferreira, Tiago H., et al.
Publicado: (2017)

Boron neutron capture therapy: Current status and future perspectives
por: Dymova, Mayya Alexandrovna, et al.
Publicado: (2020)

Boron Neutron Capture Therapy: A Review of Clinical Applications
por: Malouff, Timothy D., et al.
Publicado: (2021)

The basis and advances in clinical application of boron neutron capture therapy
por: He, Huifang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2ddsudlmdeio8e0194r9rn50i5