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Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort study
INTRODUCTION: As COVID-19 continues to spread globally and within Mozambique, its impact among immunosuppressed persons, specifically persons living with HIV (PLHIV), and on the health system is unknown in the country. The ‘COVid and hIV’ (COVIV) study aims to investigate: (1) the seroprevalence and...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BMJ Publishing Group
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254687/ https://www.ncbi.nlm.nih.gov/pubmed/37280029 http://dx.doi.org/10.1136/bmjopen-2022-068988 |
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author | De Schacht, Caroline Nhacule, Edna Belo, Celso Young, Peter W Bhatt, Nilesh Júnior, Faustino Pimentel De Gusmão, Eduarda Muquingue, Humberto Muteerwa, Ana Bila, Dulce Ouenzar, Mohammed A Madede, Tavares Cumbane, Reginalda Amorim, Gustavo Viegas, Edna |
author_facet | De Schacht, Caroline Nhacule, Edna Belo, Celso Young, Peter W Bhatt, Nilesh Júnior, Faustino Pimentel De Gusmão, Eduarda Muquingue, Humberto Muteerwa, Ana Bila, Dulce Ouenzar, Mohammed A Madede, Tavares Cumbane, Reginalda Amorim, Gustavo Viegas, Edna |
author_sort | De Schacht, Caroline |
collection | PubMed |
description | INTRODUCTION: As COVID-19 continues to spread globally and within Mozambique, its impact among immunosuppressed persons, specifically persons living with HIV (PLHIV), and on the health system is unknown in the country. The ‘COVid and hIV’ (COVIV) study aims to investigate: (1) the seroprevalence and seroincidence of SARS-CoV-2 among PLHIV and healthcare workers providing HIV services; (2) knowledge, attitudes, practices and perceptions regarding SARS-CoV-2 infection; (3) the pandemic’s impact on HIV care continuum outcomes and (4) facility level compliance with national COVID-19 guidelines. METHODS AND ANALYSIS: A multimethod study will be conducted in a maximum of 11 health facilities across Mozambique, comprising four components: (1) a cohort study among PLHIV and healthcare workers providing HIV services to determine the seroprevalence and seroincidence of SARS-CoV-2, (2) a structured survey to assess knowledge, attitudes, perceptions and practices regarding COVID-19 disease, (3) analysis of aggregated patient data to evaluate retention in HIV services among PLHIV, (4) an assessment of facility implementation of infection prevention and control measures. ETHICS AND DISSEMINATION: Ethical approval was obtained from the National Health Bioethics Committee, and institutional review boards of implementing partners. Study findings will be discussed with local and national health authorities and key stakeholders and will be disseminated in clinical and scientific forums. TRIAL REGISTRATION NUMBER: NCT05022407. |
format | Online Article Text |
id | pubmed-10254687 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-102546872023-06-10 Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort study De Schacht, Caroline Nhacule, Edna Belo, Celso Young, Peter W Bhatt, Nilesh Júnior, Faustino Pimentel De Gusmão, Eduarda Muquingue, Humberto Muteerwa, Ana Bila, Dulce Ouenzar, Mohammed A Madede, Tavares Cumbane, Reginalda Amorim, Gustavo Viegas, Edna BMJ Open Epidemiology INTRODUCTION: As COVID-19 continues to spread globally and within Mozambique, its impact among immunosuppressed persons, specifically persons living with HIV (PLHIV), and on the health system is unknown in the country. The ‘COVid and hIV’ (COVIV) study aims to investigate: (1) the seroprevalence and seroincidence of SARS-CoV-2 among PLHIV and healthcare workers providing HIV services; (2) knowledge, attitudes, practices and perceptions regarding SARS-CoV-2 infection; (3) the pandemic’s impact on HIV care continuum outcomes and (4) facility level compliance with national COVID-19 guidelines. METHODS AND ANALYSIS: A multimethod study will be conducted in a maximum of 11 health facilities across Mozambique, comprising four components: (1) a cohort study among PLHIV and healthcare workers providing HIV services to determine the seroprevalence and seroincidence of SARS-CoV-2, (2) a structured survey to assess knowledge, attitudes, perceptions and practices regarding COVID-19 disease, (3) analysis of aggregated patient data to evaluate retention in HIV services among PLHIV, (4) an assessment of facility implementation of infection prevention and control measures. ETHICS AND DISSEMINATION: Ethical approval was obtained from the National Health Bioethics Committee, and institutional review boards of implementing partners. Study findings will be discussed with local and national health authorities and key stakeholders and will be disseminated in clinical and scientific forums. TRIAL REGISTRATION NUMBER: NCT05022407. BMJ Publishing Group 2023-06-06 /pmc/articles/PMC10254687/ /pubmed/37280029 http://dx.doi.org/10.1136/bmjopen-2022-068988 Text en © Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Epidemiology De Schacht, Caroline Nhacule, Edna Belo, Celso Young, Peter W Bhatt, Nilesh Júnior, Faustino Pimentel De Gusmão, Eduarda Muquingue, Humberto Muteerwa, Ana Bila, Dulce Ouenzar, Mohammed A Madede, Tavares Cumbane, Reginalda Amorim, Gustavo Viegas, Edna Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort study |
title | Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort study |
title_full | Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort study |
title_fullStr | Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort study |
title_full_unstemmed | Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort study |
title_short | Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort study |
title_sort | measuring the burden of sars-cov-2 infection among persons living with hiv and healthcare workers and its impact on service delivery in mozambique: protocol of a prospective cohort study |
topic | Epidemiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254687/ https://www.ncbi.nlm.nih.gov/pubmed/37280029 http://dx.doi.org/10.1136/bmjopen-2022-068988 |
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