Protocol for a comprehensive prospective cohort study of trio-based whole-genome sequencing for underlying cancer predisposition in paediatric and adolescent patients newly diagnosed with cancer: the PREDICT study

INTRODUCTION: Identifying an underlying germline cancer predisposition (CP) in a child with cancer has potentially significant implications for both the child and biological relatives. Cohort studies indicate that 10%–15% of paediatric cancer patients carry germline pathogenic or likely pathogenic v...

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Detalles Bibliográficos
Autores principales: Fuentes Bolanos, Noemi Auxiliadora, Padhye, Bhavna, Daley, Macabe, Hunter, Jacqueline, Hetherington, Kate, Warby, Meera, Courtney, Eliza, Kirk, Judy, Josephi-Taylor, Sarah, Chen, Yuyan, Alvaro, Frank, Barlow-Stewart, Kristine, Wong-Erasmus, Marie, Barahona, Paulette, Ajuyah, Pamela, Altekoester, Ann-Kristin, Tyrrell, Vanessa J, Lau, Loretta M S, Wakefield, Claire, Sylvester, Dianne, Tucker, Katherine, Pinese, Mark, Dalla Pozza, Luciano, O’Brien, Tracey A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10254808/
https://www.ncbi.nlm.nih.gov/pubmed/37253493
http://dx.doi.org/10.1136/bmjopen-2022-070082

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