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Genetic dissection of HLA-DRB1*15:01 and XL9 region variants in Japanese patients with systemic lupus erythematosus: primary role for HLA-DRB1*15:01

OBJECTIVE: Major histocompatibility complex strongly contributes to susceptibility to systemic lupus erythematosus (SLE). In the European populations, HLA-DRB1*03:01 and DRB1*15:01 are susceptibility alleles, but C4 locus was reported to account for the association of DRB1*03:01. With respect to DRB...

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Detalles Bibliográficos
Autores principales: Kawasaki, Aya, Kusumawati, Premita Ari, Kawamura, Yuka, Kondo, Yuya, Kusaoi, Makio, Amano, Hirofumi, Kusanagi, Yasuyoshi, Itoh, Kenji, Fujimoto, Takashi, Tamura, Naoto, Hashimoto, Hiroshi, Matsumoto, Isao, Sumida, Takayuki, Tsuchiya, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255040/
https://www.ncbi.nlm.nih.gov/pubmed/37258043
http://dx.doi.org/10.1136/rmdopen-2023-003214