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Outcomes and a prognostic classifier in patients with microsatellite instability-high metastatic gastric cancer receiving PD-1 blockade
BACKGROUND: Subgroup analyses of randomized trials suggest the superiority of immune checkpoint inhibitor-based therapy over chemotherapy in patients with mismatch-repair deficient (dMMR) and/or microsatellite instability-high (MSI-high) advanced gastric or gastroesophageal junction adenocarcinoma....
Autores principales: | Randon, Giovanni, Aoki, Yu, Cohen, Romain, Provenzano, Leonardo, Nasca, Vincenzo, Klempner, Samuel J, Maron, Steven B, Cerantola, Riccardo, Chao, Joseph, Fornaro, Lorenzo, Ferrari Bravo, Walter, Ghelardi, Filippo, Ambrosini, Margherita, Manca, Paolo, Salati, Massimiliano, Kawazoe, Akihito, Zhu, Valerie, Cowzer, Darren, Genovesi, Virginia, Lonardi, Sara, Shitara, Kohei, André, Thierry, Pietrantonio, Filippo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255232/ https://www.ncbi.nlm.nih.gov/pubmed/37277193 http://dx.doi.org/10.1136/jitc-2023-007104 |
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