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Cell surface marker-based capture of neoantigen-reactive CD8(+) T-cell receptors from metastatic tumor digests

BACKGROUND: Cellular immunotherapies using autologous tumor-infiltrating lymphocytes (TIL) can induce durable regression of epithelial cancers in selected patients with treatment-refractory metastatic disease. As the genetic engineering of T cells with tumor-reactive T-cell receptors (TCRs) comes to...

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Detalles Bibliográficos
Autores principales:	Chatani, Praveen D, Lowery, Frank J, Parikh, Neilesh B, Hitscherich, Kyle J, Yossef, Rami, Hill, Victoria, Gartner, Jared J, Paria, Biman, Florentin, Maria, Ray, Satyajit, Bera, Alakesh, Parkhust, Maria, Robbins, Paul, Krishna, Sri, Rosenberg, Steven A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2023
Materias:	Immune Cell Therapies and Immune Cell Engineering
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255266/ https://www.ncbi.nlm.nih.gov/pubmed/37258038 http://dx.doi.org/10.1136/jitc-2022-006264

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