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Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone

A relationship may exist between selenium and kidney calculi, but there is a lack of research in this field at present. Our study explored the relationship between the serum selenium level and a medical history of adult kidney calculi. We utilized data from the National Health and Nutrition Examinat...

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Autores principales: Wang, Anni, Wang, Ningrui, Zhang, Dongfeng, Wen, Jing, Wang, Weijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255404/
https://www.ncbi.nlm.nih.gov/pubmed/37299511
http://dx.doi.org/10.3390/nu15112549
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author Wang, Anni
Wang, Ningrui
Zhang, Dongfeng
Wen, Jing
Wang, Weijing
author_facet Wang, Anni
Wang, Ningrui
Zhang, Dongfeng
Wen, Jing
Wang, Weijing
author_sort Wang, Anni
collection PubMed
description A relationship may exist between selenium and kidney calculi, but there is a lack of research in this field at present. Our study explored the relationship between the serum selenium level and a medical history of adult kidney calculi. We utilized data from the National Health and Nutrition Examination Survey conducted between 2011 and 2016. Participants self-reported their history of kidney stones, while serum selenium levels were measured using inductively coupled plasma dynamic reaction cell mass spectrometry. Our findings indicate a negative correlation between serum selenium levels and the risk of kidney stone history. In the multiple-adjusted model, the lowest serum selenium level group had a higher risk than the other groups. The odds ratio (95% confidence interval) of ever having kidney stones for the highest serum selenium level group was 0.54 (0.33–0.88). In the results of stratified analysis, this relationship was still significant in the groups of women and those 40–59 years. We also found that as a nonlinear dose–response relationship between serum selenium levels and the history of kidney stones disease. In our research, we found that people with higher serum selenium levels had a lower risk of having a history of kidney stones. We concluded that selenium may have a protective effect on kidney stones. In the future, more population studies are needed to explore the relationship between selenium and kidney stones.
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spelling pubmed-102554042023-06-10 Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone Wang, Anni Wang, Ningrui Zhang, Dongfeng Wen, Jing Wang, Weijing Nutrients Article A relationship may exist between selenium and kidney calculi, but there is a lack of research in this field at present. Our study explored the relationship between the serum selenium level and a medical history of adult kidney calculi. We utilized data from the National Health and Nutrition Examination Survey conducted between 2011 and 2016. Participants self-reported their history of kidney stones, while serum selenium levels were measured using inductively coupled plasma dynamic reaction cell mass spectrometry. Our findings indicate a negative correlation between serum selenium levels and the risk of kidney stone history. In the multiple-adjusted model, the lowest serum selenium level group had a higher risk than the other groups. The odds ratio (95% confidence interval) of ever having kidney stones for the highest serum selenium level group was 0.54 (0.33–0.88). In the results of stratified analysis, this relationship was still significant in the groups of women and those 40–59 years. We also found that as a nonlinear dose–response relationship between serum selenium levels and the history of kidney stones disease. In our research, we found that people with higher serum selenium levels had a lower risk of having a history of kidney stones. We concluded that selenium may have a protective effect on kidney stones. In the future, more population studies are needed to explore the relationship between selenium and kidney stones. MDPI 2023-05-30 /pmc/articles/PMC10255404/ /pubmed/37299511 http://dx.doi.org/10.3390/nu15112549 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Anni
Wang, Ningrui
Zhang, Dongfeng
Wen, Jing
Wang, Weijing
Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone
title Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone
title_full Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone
title_fullStr Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone
title_full_unstemmed Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone
title_short Relationship between Serum Selenium Level and Self-Reported History of Kidney Stone
title_sort relationship between serum selenium level and self-reported history of kidney stone
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255404/
https://www.ncbi.nlm.nih.gov/pubmed/37299511
http://dx.doi.org/10.3390/nu15112549
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