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Synthesis, Characterization, Properties, and Biomedical Application of Chitosan-Based Hydrogels

The prospective applications of chitosan-based hydrogels (CBHs), a category of biocompatible and biodegradable materials, in biomedical disciplines such as tissue engineering, wound healing, drug delivery, and biosensing have garnered great interest. The synthesis and characterization processes used...

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Autores principales: Ye, Ruixi, Liu, Siyu, Zhu, Wenkai, Li, Yurong, Huang, Long, Zhang, Guozheng, Zhang, Yeshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255636/
https://www.ncbi.nlm.nih.gov/pubmed/37299281
http://dx.doi.org/10.3390/polym15112482
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author Ye, Ruixi
Liu, Siyu
Zhu, Wenkai
Li, Yurong
Huang, Long
Zhang, Guozheng
Zhang, Yeshun
author_facet Ye, Ruixi
Liu, Siyu
Zhu, Wenkai
Li, Yurong
Huang, Long
Zhang, Guozheng
Zhang, Yeshun
author_sort Ye, Ruixi
collection PubMed
description The prospective applications of chitosan-based hydrogels (CBHs), a category of biocompatible and biodegradable materials, in biomedical disciplines such as tissue engineering, wound healing, drug delivery, and biosensing have garnered great interest. The synthesis and characterization processes used to create CBHs play a significant role in determining their characteristics and effectiveness. The qualities of CBHs might be greatly influenced by tailoring the manufacturing method to get certain traits, including porosity, swelling, mechanical strength, and bioactivity. Additionally, characterization methods aid in gaining access to the microstructures and properties of CBHs. Herein, this review provides a comprehensive assessment of the state-of-the-art with a focus on the affiliation between particular properties and domains in biomedicine. Moreover, this review highlights the beneficial properties and wide application of stimuli-responsive CBHs. The main obstacles and prospects for the future of CBH development for biomedical applications are also covered in this review.
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spelling pubmed-102556362023-06-10 Synthesis, Characterization, Properties, and Biomedical Application of Chitosan-Based Hydrogels Ye, Ruixi Liu, Siyu Zhu, Wenkai Li, Yurong Huang, Long Zhang, Guozheng Zhang, Yeshun Polymers (Basel) Review The prospective applications of chitosan-based hydrogels (CBHs), a category of biocompatible and biodegradable materials, in biomedical disciplines such as tissue engineering, wound healing, drug delivery, and biosensing have garnered great interest. The synthesis and characterization processes used to create CBHs play a significant role in determining their characteristics and effectiveness. The qualities of CBHs might be greatly influenced by tailoring the manufacturing method to get certain traits, including porosity, swelling, mechanical strength, and bioactivity. Additionally, characterization methods aid in gaining access to the microstructures and properties of CBHs. Herein, this review provides a comprehensive assessment of the state-of-the-art with a focus on the affiliation between particular properties and domains in biomedicine. Moreover, this review highlights the beneficial properties and wide application of stimuli-responsive CBHs. The main obstacles and prospects for the future of CBH development for biomedical applications are also covered in this review. MDPI 2023-05-27 /pmc/articles/PMC10255636/ /pubmed/37299281 http://dx.doi.org/10.3390/polym15112482 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ye, Ruixi
Liu, Siyu
Zhu, Wenkai
Li, Yurong
Huang, Long
Zhang, Guozheng
Zhang, Yeshun
Synthesis, Characterization, Properties, and Biomedical Application of Chitosan-Based Hydrogels
title Synthesis, Characterization, Properties, and Biomedical Application of Chitosan-Based Hydrogels
title_full Synthesis, Characterization, Properties, and Biomedical Application of Chitosan-Based Hydrogels
title_fullStr Synthesis, Characterization, Properties, and Biomedical Application of Chitosan-Based Hydrogels
title_full_unstemmed Synthesis, Characterization, Properties, and Biomedical Application of Chitosan-Based Hydrogels
title_short Synthesis, Characterization, Properties, and Biomedical Application of Chitosan-Based Hydrogels
title_sort synthesis, characterization, properties, and biomedical application of chitosan-based hydrogels
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255636/
https://www.ncbi.nlm.nih.gov/pubmed/37299281
http://dx.doi.org/10.3390/polym15112482
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