Early Life Obesity Increases Neuroinflammation, Amyloid Beta Deposition, and Cognitive Decline in a Mouse Model of Alzheimer’s Disease

Obesity, a known risk factor of Alzheimer’s disease (AD), increases the activation of microglia, leading to a proinflammatory phenotype. Our previous work shows that a high fat diet (HFD) can cause neuroinflammation and cognitive decline in mice. We hypothesized that proinflammatory activation of br...

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Detalles Bibliográficos
Autores principales: So, Simon W., Fleming, Kendra M., Nixon, Joshua P., Butterick, Tammy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255742/
https://www.ncbi.nlm.nih.gov/pubmed/37299457
http://dx.doi.org/10.3390/nu15112494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10255742/
https://www.ncbi.nlm.nih.gov/pubmed/37299457
http://dx.doi.org/10.3390/nu15112494

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