HPIP is an essential scaffolding protein running through the EGFR-RAS-ERK pathway and drives tumorigenesis

The EGFR-RAS-ERK pathway plays a key role in cancer development and progression. However, the integral assembly of EGFR-RAS-ERK signaling complexes from the upstream component EGFR to the downstream component ERK is largely unknown. Here, we show that hematopoietic PBX-interacting protein (HPIP) int...

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Detalles Bibliográficos
Autores principales: Jiang, Qiwei, Zhang, Deyu, Liu, Juan, Liang, Chaoyang, Yang, Ronghui, Zhang, Cheng, Wu, Jun, Lin, Jing, Ye, Tianxing, Ding, Lihua, Li, Jianbin, Gao, Shan, Li, Binghui, Ye, Qinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256163/
https://www.ncbi.nlm.nih.gov/pubmed/37294756
http://dx.doi.org/10.1126/sciadv.ade1155

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