IFITM1 enhances nonenveloped viral RNA replication by facilitating cholesterol transport to the Golgi

Aichi virus (AiV), a small non-enveloped RNA virus, hijacks the endoplasmic reticulum (ER)–Golgi cholesterol transport machinery to form cholesterol-rich replication sites originating from Golgi membranes. Interferon-induced transmembrane proteins (IFITMs) are antiviral restriction factors, whose in...

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Detalles Bibliográficos
Autores principales: ISHIKAWA-Sasaki, Kumiko, Murata, Takayuki, Sasaki, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256215/
https://www.ncbi.nlm.nih.gov/pubmed/37252940
http://dx.doi.org/10.1371/journal.ppat.1011383

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