A SiO(2) Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose

A novel enzyme-based biosensor for glucose detection is successfully developed using layer-by-layer assembly technology. The introduction of commercially available SiO(2) was found to be a facile way to improve overall electrochemical stability. After 30 CV cycles, the proposed biosensor could retai...

Descripción completa

Detalles Bibliográficos
Autores principales: Mei, Li, Yang, Yiting, Li, Jiagen, Shang, Shuyong, Fu, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256442/
https://www.ncbi.nlm.nih.gov/pubmed/37304841
http://dx.doi.org/10.1155/2023/6620613
_version_ 1785057104361422848
author Mei, Li
Yang, Yiting
Li, Jiagen
Shang, Shuyong
Fu, Xiaohong
author_facet Mei, Li
Yang, Yiting
Li, Jiagen
Shang, Shuyong
Fu, Xiaohong
author_sort Mei, Li
collection PubMed
description A novel enzyme-based biosensor for glucose detection is successfully developed using layer-by-layer assembly technology. The introduction of commercially available SiO(2) was found to be a facile way to improve overall electrochemical stability. After 30 CV cycles, the proposed biosensor could retain 95% of its original current. The biosensor presents good detection stability and reproducibility with the detection concentration range of 1.96 × 10(−9) to 7.24 × 10(−7) M. This study demonstrated that the hybridization of cheap inorganic nanoparticles was a useful method in preparing high-performance biosensors with a much lower cost.
format Online
Article
Text
id pubmed-10256442
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-102564422023-06-10 A SiO(2) Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose Mei, Li Yang, Yiting Li, Jiagen Shang, Shuyong Fu, Xiaohong Int J Anal Chem Research Article A novel enzyme-based biosensor for glucose detection is successfully developed using layer-by-layer assembly technology. The introduction of commercially available SiO(2) was found to be a facile way to improve overall electrochemical stability. After 30 CV cycles, the proposed biosensor could retain 95% of its original current. The biosensor presents good detection stability and reproducibility with the detection concentration range of 1.96 × 10(−9) to 7.24 × 10(−7) M. This study demonstrated that the hybridization of cheap inorganic nanoparticles was a useful method in preparing high-performance biosensors with a much lower cost. Hindawi 2023-06-02 /pmc/articles/PMC10256442/ /pubmed/37304841 http://dx.doi.org/10.1155/2023/6620613 Text en Copyright © 2023 Li Mei et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mei, Li
Yang, Yiting
Li, Jiagen
Shang, Shuyong
Fu, Xiaohong
A SiO(2) Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose
title A SiO(2) Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose
title_full A SiO(2) Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose
title_fullStr A SiO(2) Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose
title_full_unstemmed A SiO(2) Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose
title_short A SiO(2) Hybrid Enzyme-Based Biosensor with Enhanced Electrochemical Stability for Accuracy Detection of Glucose
title_sort sio(2) hybrid enzyme-based biosensor with enhanced electrochemical stability for accuracy detection of glucose
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256442/
https://www.ncbi.nlm.nih.gov/pubmed/37304841
http://dx.doi.org/10.1155/2023/6620613
work_keys_str_mv AT meili asio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose
AT yangyiting asio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose
AT lijiagen asio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose
AT shangshuyong asio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose
AT fuxiaohong asio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose
AT meili sio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose
AT yangyiting sio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose
AT lijiagen sio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose
AT shangshuyong sio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose
AT fuxiaohong sio2hybridenzymebasedbiosensorwithenhancedelectrochemicalstabilityforaccuracydetectionofglucose

Ejemplares similares