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Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism

Gastric cancer (GC) is among the most lethal malignancies due to its poor early diagnosis and high metastasis rate, and new therapeutic targets are urgently needed to develop effective anti-GC drugs. Glutathione peroxidase-2 (GPx2) plays various roles in tumor progression and patient survival. Herei...

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Detalles Bibliográficos
Autores principales: Xu, Handong, Hu, Can, Wang, Yi, Shi, Yunfu, Yuan, Li, Xu, Jingli, Zhang, Yanqiang, Chen, Jiahui, Wei, Qin, Qin, Jiangjiang, Xu, Zhiyuan, Cheng, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256612/
https://www.ncbi.nlm.nih.gov/pubmed/37138031
http://dx.doi.org/10.1038/s41388-023-02708-4