Pharmacokinetics and Safety of Cotadutide, a GLP-1 and Glucagon Receptor Dual Agonist, in Individuals with Renal Impairment: A Single-Dose, Phase I, Bridging Study

BACKGROUND AND OBJECTIVE: Cotadutide is a balanced glucagon-like peptide-1 and glucagon receptor dual agonist under development for the treatment of non-alcoholic steatohepatitis and type 2 diabetes with chronic kidney disease. We evaluated the pharmacokinetics (PK), safety and immunogenicity of a s...

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Detalles Bibliográficos
Autores principales: Klein, Gernot, Petrone, Marcella, Yang, Ye, Hoang, Thuong, Hazlett, Sheila, Hansen, Lars, Flor, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256642/
https://www.ncbi.nlm.nih.gov/pubmed/37140727
http://dx.doi.org/10.1007/s40262-023-01239-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256642/
https://www.ncbi.nlm.nih.gov/pubmed/37140727
http://dx.doi.org/10.1007/s40262-023-01239-1

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