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Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo

VX is a highly toxic organophosphorus nerve agent that reacts with a variety of endogenous proteins such as serum albumin under formation of adducts that can be targeted by analytical methods for biomedical verification of exposure. Albumin is phosphonylated by the ethyl methylphosphonic acid moiety...

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Detalles Bibliográficos
Autores principales:	Kranawetvogl, Tamara, Kranawetvogl, Andreas, Scheidegger, Lisa, Wille, Timo, Steinritz, Dirk, Worek, Franz, Thiermann, Horst, John, Harald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Analytical Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256656/ https://www.ncbi.nlm.nih.gov/pubmed/37264164 http://dx.doi.org/10.1007/s00204-023-03521-4

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