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In vivo PAR-CLIP (viP-CLIP) of liver TIAL1 unveils targets regulating cholesterol synthesis and secretion

System-wide cross-linking and immunoprecipitation (CLIP) approaches have unveiled regulatory mechanisms of RNA-binding proteins (RBPs) mainly in cultured cells due to limitations in the cross-linking efficiency of tissues. Here, we describe viP-CLIP (in vivo PAR-CLIP), a method capable of identifyin...

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Detalles Bibliográficos
Autores principales: Vatandaslar, Hasan, Garzia, Aitor, Meyer, Cindy, Godbersen, Svenja, Brandt, Laura T. L., Griesbach, Esther, Chao, Jeffrey A., Tuschl, Thomas, Stoffel, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256721/
https://www.ncbi.nlm.nih.gov/pubmed/37296170
http://dx.doi.org/10.1038/s41467-023-39135-8