Muscleblind-like proteins use modular domains to localize RNAs by riding kinesins and docking to membranes

RNA binding proteins (RBPs) act as critical facilitators of spatially regulated gene expression. Muscleblind-like (MBNL) proteins, implicated in myotonic dystrophy and cancer, localize RNAs to myoblast membranes and neurites through unknown mechanisms. We find that MBNL forms motile and anchored gra...

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Detalles Bibliográficos
Autores principales: Hildebrandt, Ryan P., Moss, Kathryn R., Janusz-Kaminska, Aleksandra, Knudson, Luke A., Denes, Lance T., Saxena, Tanvi, Boggupalli, Devi Prasad, Li, Zhuangyue, Lin, Kun, Bassell, Gary J., Wang, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256740/
https://www.ncbi.nlm.nih.gov/pubmed/37296096
http://dx.doi.org/10.1038/s41467-023-38923-6

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