Group B Streptococcus Cas9 variants provide insight into programmable gene repression and CRISPR-Cas transcriptional effects

Group B Streptococcus (GBS; S. agalactiae) causes chorioamnionitis, neonatal sepsis, and can also cause disease in healthy or immunocompromised adults. GBS possesses a type II-A CRISPR-Cas9 system, which defends against foreign DNA within the bacterial cell. Several recent publications have shown th...

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Detalles Bibliográficos
Autores principales: Gopalakrishna, Kathyayini P., Hillebrand, Gideon H., Bhavana, Venkata H., Elder, Jordan L., D’Mello, Adonis, Tettelin, Hervé, Hooven, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256743/
https://www.ncbi.nlm.nih.gov/pubmed/37296208
http://dx.doi.org/10.1038/s42003-023-04994-w

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