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Histone H2A Lys130 acetylation epigenetically regulates androgen production in prostate cancer

The testicular androgen biosynthesis is well understood, however, how cancer cells gauge dwindling androgen to dexterously initiate its de novo synthesis remained elusive. We uncover dual-phosphorylated form of sterol regulatory element-binding protein 1 (SREBF1), pY673/951-SREBF1 that acts as an an...

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Detalles Bibliográficos
Autores principales:	Nguyen, Thanh, Sridaran, Dhivya, Chouhan, Surbhi, Weimholt, Cody, Wilson, Audrey, Luo, Jingqin, Li, Tiandao, Koomen, John, Fang, Bin, Putluri, Nagireddy, Sreekumar, Arun, Feng, Felix Y., Mahajan, Kiran, Mahajan, Nupam P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256812/ https://www.ncbi.nlm.nih.gov/pubmed/37296155 http://dx.doi.org/10.1038/s41467-023-38887-7

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