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Article Topic: Neuropathies Due to Infections and Antimicrobial Treatments

PURPOSE OF EVIEW: The aim of this review is to discuss the presentation, diagnosis, and management of polyneuropathy (PN) in selected infections. Overall, most infection related PNs are an indirect consequence of immune activation rather than a direct result of peripheral nerve infection,  Schwann c...

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Autores principales: De León, Andrés M., Garcia-Santibanez, Rocio, Harrison, Taylor B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256960/
https://www.ncbi.nlm.nih.gov/pubmed/37360749
http://dx.doi.org/10.1007/s11940-023-00756-5
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author De León, Andrés M.
Garcia-Santibanez, Rocio
Harrison, Taylor B.
author_facet De León, Andrés M.
Garcia-Santibanez, Rocio
Harrison, Taylor B.
author_sort De León, Andrés M.
collection PubMed
description PURPOSE OF EVIEW: The aim of this review is to discuss the presentation, diagnosis, and management of polyneuropathy (PN) in selected infections. Overall, most infection related PNs are an indirect consequence of immune activation rather than a direct result of peripheral nerve infection,  Schwann cell infection, or toxin production, though note this review will describe infections that cause PN through all these mechanisms. Rather than dividing them by each infectious agent separately, we have grouped the infectious neuropathies according to their presenting phenotype, to serve as a guide to clinicians. Finally, toxic neuropathies related to antimicrobials are briefly summarized. RECENT FINDINGS: While PN from many infections is decreasing, increasing evidence links infections to variants of GBS. Incidence of neuropathies secondary to use of HIV therapy has decreased over the last few years. SUMMARY: In this manuscript, a general overview of the more common infectious causes of PN will be discussed, dividing them across clinical phenotypes: large- and small-fiber polyneuropathy, Guillain-Barré syndrome (GBS), mononeuritis multiplex, and autonomic neuropathy. Rare but important infectious causes are also discussed.
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spelling pubmed-102569602023-06-12 Article Topic: Neuropathies Due to Infections and Antimicrobial Treatments De León, Andrés M. Garcia-Santibanez, Rocio Harrison, Taylor B. Curr Treat Options Neurol Article PURPOSE OF EVIEW: The aim of this review is to discuss the presentation, diagnosis, and management of polyneuropathy (PN) in selected infections. Overall, most infection related PNs are an indirect consequence of immune activation rather than a direct result of peripheral nerve infection,  Schwann cell infection, or toxin production, though note this review will describe infections that cause PN through all these mechanisms. Rather than dividing them by each infectious agent separately, we have grouped the infectious neuropathies according to their presenting phenotype, to serve as a guide to clinicians. Finally, toxic neuropathies related to antimicrobials are briefly summarized. RECENT FINDINGS: While PN from many infections is decreasing, increasing evidence links infections to variants of GBS. Incidence of neuropathies secondary to use of HIV therapy has decreased over the last few years. SUMMARY: In this manuscript, a general overview of the more common infectious causes of PN will be discussed, dividing them across clinical phenotypes: large- and small-fiber polyneuropathy, Guillain-Barré syndrome (GBS), mononeuritis multiplex, and autonomic neuropathy. Rare but important infectious causes are also discussed. Springer US 2023-06-10 /pmc/articles/PMC10256960/ /pubmed/37360749 http://dx.doi.org/10.1007/s11940-023-00756-5 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
De León, Andrés M.
Garcia-Santibanez, Rocio
Harrison, Taylor B.
Article Topic: Neuropathies Due to Infections and Antimicrobial Treatments
title Article Topic: Neuropathies Due to Infections and Antimicrobial Treatments
title_full Article Topic: Neuropathies Due to Infections and Antimicrobial Treatments
title_fullStr Article Topic: Neuropathies Due to Infections and Antimicrobial Treatments
title_full_unstemmed Article Topic: Neuropathies Due to Infections and Antimicrobial Treatments
title_short Article Topic: Neuropathies Due to Infections and Antimicrobial Treatments
title_sort article topic: neuropathies due to infections and antimicrobial treatments
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10256960/
https://www.ncbi.nlm.nih.gov/pubmed/37360749
http://dx.doi.org/10.1007/s11940-023-00756-5
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