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Discovery of senolytics using machine learning

Cellular senescence is a stress response involved in ageing and diverse disease processes including cancer, type-2 diabetes, osteoarthritis and viral infection. Despite growing interest in targeted elimination of senescent cells, only few senolytics are known due to the lack of well-characterised mo...

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Detalles Bibliográficos
Autores principales: Smer-Barreto, Vanessa, Quintanilla, Andrea, Elliott, Richard J. R., Dawson, John C., Sun, Jiugeng, Campa, Víctor M., Lorente-Macías, Álvaro, Unciti-Broceta, Asier, Carragher, Neil O., Acosta, Juan Carlos, Oyarzún, Diego A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257182/
https://www.ncbi.nlm.nih.gov/pubmed/37301862
http://dx.doi.org/10.1038/s41467-023-39120-1

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