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Spatiotemporal pharmacometabolomics based on ambient mass spectrometry imaging to evaluate the metabolism and hepatotoxicity of amiodarone in HepG2 spheroids

Three-dimensional (3D) cell spheroid models combined with mass spectrometry imaging (MSI) enables innovative investigation of in vivo-like biological processes under different physiological and pathological conditions. Herein, airflow-assisted desorption electrospray ionization-MSI (AFADESI-MSI) was...

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Detalles Bibliográficos
Autores principales:	Li, Limei, Zang, Qingce, Li, Xinzhu, Zhu, Ying, Wen, Shanjing, He, Jiuming, Zhang, Ruiping, Abliz, Zeper
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Xi'an Jiaotong University 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257197/ https://www.ncbi.nlm.nih.gov/pubmed/37305784 http://dx.doi.org/10.1016/j.jpha.2023.04.007

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