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MiR-494 induces metabolic changes through G6pc targeting and modulates sorafenib response in hepatocellular carcinoma

BACKGROUND: Metabolic reprogramming is a well-known marker of cancer, and it represents an early event during hepatocellular carcinoma (HCC) development. The recent approval of several molecular targeted agents has revolutionized the management of advanced HCC patients. Nevertheless, the lack of cir...

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Detalles Bibliográficos
Autores principales: Bergamini, Christian, Leoni, Ilaria, Rizzardi, Nicola, Melli, Mattia, Galvani, Giuseppe, Coada, Camelia Alexandra, Giovannini, Catia, Monti, Elisa, Liparulo, Irene, Valenti, Francesca, Ferracin, Manuela, Ravaioli, Matteo, Cescon, Matteo, Vasuri, Francesco, Piscaglia, Fabio, Negrini, Massimo, Stefanelli, Claudio, Fato, Romana, Gramantieri, Laura, Fornari, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257313/
https://www.ncbi.nlm.nih.gov/pubmed/37301960
http://dx.doi.org/10.1186/s13046-023-02718-w