Cargando…
Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009–2019)
BACKGROUND: Although ocular findings in diabetic patients are well described, prevalence data for those is unknown. AIM: To describe the prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus. METHODS: Medical records from diabetic dogs assessed by the ophth...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculty of Veterinary Medicine
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257449/ https://www.ncbi.nlm.nih.gov/pubmed/37304611 http://dx.doi.org/10.5455/OVJ.2023.v13.i5.15 |
_version_ | 1785057304438112256 |
---|---|
author | Cantero, Francisco Ortillés, Ángel Teresa Peña, M. Leiva, Marta |
author_facet | Cantero, Francisco Ortillés, Ángel Teresa Peña, M. Leiva, Marta |
author_sort | Cantero, Francisco |
collection | PubMed |
description | BACKGROUND: Although ocular findings in diabetic patients are well described, prevalence data for those is unknown. AIM: To describe the prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus. METHODS: Medical records from diabetic dogs assessed by the ophthalmology and the internal medicine services at the Veterinary Teaching Hospital of the Autonomous University of Barcelona were reviewed (2009–2019). RESULTS: Seventy-five dogs (150 eyes) of both genders (51/75 females; 68% and 24/75 males; 32%) and a mean age of 9.37 ± 2.43 years, were included. The most common ocular findings were cataracts (146/150; 97.3%), vitreous degeneration (45/98; 45.9%), anterior uveitis (47/150; 31.3%), aqueous deficiency dry eye (ADDE) (33/150; 22%), diffuse corneal edema (31/150; 20.7%), non-proliferative retinopathy (13/98; 13.3%), and lipid keratopathy (9/150; 6%). The most prevalent type of cataracts observed (78/146; 53.4%) was intumescent, which was commonly accompanied by non-proliferative retinopathy (p = 0.003). Among the diabetic dogs, blood glucose levels were statistically higher in dogs with non-proliferative retinopathy or anterior uveitis (p < 0.005). CONCLUSIONS: Ocular complications of diabetes mellitus in dogs are numerous, being the most frequent intumescent cataracts, vitreous degeneration, anterior uveitis, ADDE, diffuse corneal edema, and non-proliferative retinopathy. This high prevalence warrants a more detailed ophthalmic evaluation in diabetic dogs especially for those undergoing cataract surgery. Furthermore, a predisposition for anterior segment inflammation and non-proliferative retinopathy is suggested when fasting plasma glucose is higher than 600 mg/dl.. |
format | Online Article Text |
id | pubmed-10257449 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Faculty of Veterinary Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-102574492023-06-11 Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009–2019) Cantero, Francisco Ortillés, Ángel Teresa Peña, M. Leiva, Marta Open Vet J Original Research BACKGROUND: Although ocular findings in diabetic patients are well described, prevalence data for those is unknown. AIM: To describe the prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus. METHODS: Medical records from diabetic dogs assessed by the ophthalmology and the internal medicine services at the Veterinary Teaching Hospital of the Autonomous University of Barcelona were reviewed (2009–2019). RESULTS: Seventy-five dogs (150 eyes) of both genders (51/75 females; 68% and 24/75 males; 32%) and a mean age of 9.37 ± 2.43 years, were included. The most common ocular findings were cataracts (146/150; 97.3%), vitreous degeneration (45/98; 45.9%), anterior uveitis (47/150; 31.3%), aqueous deficiency dry eye (ADDE) (33/150; 22%), diffuse corneal edema (31/150; 20.7%), non-proliferative retinopathy (13/98; 13.3%), and lipid keratopathy (9/150; 6%). The most prevalent type of cataracts observed (78/146; 53.4%) was intumescent, which was commonly accompanied by non-proliferative retinopathy (p = 0.003). Among the diabetic dogs, blood glucose levels were statistically higher in dogs with non-proliferative retinopathy or anterior uveitis (p < 0.005). CONCLUSIONS: Ocular complications of diabetes mellitus in dogs are numerous, being the most frequent intumescent cataracts, vitreous degeneration, anterior uveitis, ADDE, diffuse corneal edema, and non-proliferative retinopathy. This high prevalence warrants a more detailed ophthalmic evaluation in diabetic dogs especially for those undergoing cataract surgery. Furthermore, a predisposition for anterior segment inflammation and non-proliferative retinopathy is suggested when fasting plasma glucose is higher than 600 mg/dl.. Faculty of Veterinary Medicine 2023-05 2023-05-16 /pmc/articles/PMC10257449/ /pubmed/37304611 http://dx.doi.org/10.5455/OVJ.2023.v13.i5.15 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Cantero, Francisco Ortillés, Ángel Teresa Peña, M. Leiva, Marta Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009–2019) |
title | Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009–2019) |
title_full | Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009–2019) |
title_fullStr | Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009–2019) |
title_full_unstemmed | Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009–2019) |
title_short | Prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: A 10-year clinical study (2009–2019) |
title_sort | prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus: a 10-year clinical study (2009–2019) |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257449/ https://www.ncbi.nlm.nih.gov/pubmed/37304611 http://dx.doi.org/10.5455/OVJ.2023.v13.i5.15 |
work_keys_str_mv | AT canterofrancisco prevalenceofocularfindingsandtheirassociationwithglycemiaindogswithdiabetesmellitusa10yearclinicalstudy20092019 AT ortillesangel prevalenceofocularfindingsandtheirassociationwithglycemiaindogswithdiabetesmellitusa10yearclinicalstudy20092019 AT teresapenam prevalenceofocularfindingsandtheirassociationwithglycemiaindogswithdiabetesmellitusa10yearclinicalstudy20092019 AT leivamarta prevalenceofocularfindingsandtheirassociationwithglycemiaindogswithdiabetesmellitusa10yearclinicalstudy20092019 |