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Accounting for 16S rRNA copy number prediction uncertainty and its implications in bacterial diversity analyses

16S rRNA gene copy number (16S GCN) varies among bacterial species and this variation introduces potential biases to microbial diversity analyses using 16S rRNA read counts. To correct the biases, methods have been developed to predict 16S GCN. A recent study suggests that the prediction uncertainty...

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Detalles Bibliográficos
Autores principales: Gao, Yingnan, Wu, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257666/
https://www.ncbi.nlm.nih.gov/pubmed/37301942
http://dx.doi.org/10.1038/s43705-023-00266-0