Cargando…

Integrative analysis of hepatic transcriptional profiles reveals genetic regulation of atherosclerosis in hyperlipidemic Diversity Outbred-F1 mice

Atherogenesis is an insipidus but precipitating process leading to serious consequences of many cardiovascular diseases (CVD). Numerous genetic loci contributing to atherosclerosis have been identified in human genome-wide association studies, but these studies have limitations in the ability to con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Myungsuk, Huda, M. Nazmul, Evans, Levi W., Que, Excel, Gertz, Erik R., Maeda-Smithies, Nobuyo, Bennett, Brian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257719/ https://www.ncbi.nlm.nih.gov/pubmed/37301941 http://dx.doi.org/10.1038/s41598-023-35917-8

Ejemplares similares

Dissecting the Genetic Architecture of Cystatin C in Diversity Outbred Mice
por: Huda, M. Nazmul, et al.
Publicado: (2020)

Genetic Architecture Modulates Diet-Induced Hepatic mRNA and miRNA Expression Profiles in Diversity Outbred Mice
por: Que, Excel, et al.
Publicado: (2020)

Genetic architecture modulates diet-induced hepatic mRNA and miRNA expression profiles in Diversity Outbred mice
por: Que, Excel, et al.
Publicado: (2021)

Atherosclerosis in Different Vascular Locations Unbiasedly Approached with Mouse Genetics
por: Kayashima, Yukako, et al.
Publicado: (2020)

Modulating the Microbiota as a Therapeutic Intervention for Type 2 Diabetes
por: Huda, M. Nazmul, et al.
Publicado: (2021)

High-Resolution Genetic Mapping in the Diversity Outbred Mouse Population Identifies Apobec1 as a Candidate Gene for Atherosclerosis
por: Smallwood, Tangi L., et al.
Publicado: (2014)

Influence of phthalates on glucose homeostasis and atherosclerosis in hyperlipidemic mice
por: Zhou, Wei, et al.
Publicado: (2015)

Regional Variation in Genetic Control of Atherosclerosis in Hyperlipidemic Mice
por: Jones, Michael B., et al.
Publicado: (2020)

Genetic Connection between Hyperglycemia and Carotid Atherosclerosis in Hyperlipidemic Mice
por: Shi, Lisa J., et al.
Publicado: (2022)

Reduction of Stabilin-2 Contributes to a Protection Against Atherosclerosis
por: Kayashima, Yukako, et al.
Publicado: (2022)

Diversity Outbred: A New Generation of Mouse Model
por: Schmidt, Charles W.
Publicado: (2015)

Inbred or Outbred? Genetic Diversity in Laboratory Rodent Colonies
por: Brekke, Thomas D., et al.
Publicado: (2017)

Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse
por: Mayeux, Jessica M., et al.
Publicado: (2018)

Cleaning Genotype Data from Diversity Outbred Mice
por: Broman, Karl W., et al.
Publicado: (2019)

Gene expression genetics of the striatum of Diversity Outbred mice
por: Philip, Vivek M., et al.
Publicado: (2023)

Gene expression genetics of the striatum of Diversity Outbred mice
por: Philip, Vivek M., et al.
Publicado: (2023)

Ectopic expression of the Stabilin2 gene triggered by an intracisternal A particle (IAP) element in DBA/2J strain of mice
por: Maeda-Smithies, Nobuyo, et al.
Publicado: (2020)

Quantitative Trait Locus Mapping Methods for Diversity Outbred Mice
por: Gatti, Daniel M., et al.
Publicado: (2014)

Comment on “Diversity Outbred: A New Generation of Mouse Model”
por: Erren, Thomas C., et al.
Publicado: (2015)

Beneficial effects of nicotinamide on the mouse model of preeclampsia
por: Huynh, Phillip K, et al.
Publicado: (2018)

Cortistatin reduces atherosclerosis in hyperlipidemic ApoE-deficient mice and the formation of foam cells
por: Delgado-Maroto, Virginia, et al.
Publicado: (2017)

Effect of Dysferlin Deficiency on Atherosclerosis and Plasma Lipoprotein Composition Under Normal and Hyperlipidemic Conditions
por: White, Zoe, et al.
Publicado: (2021)

Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database
por: Bogue, Molly A., et al.
Publicado: (2015)

Diversity Outbred Mice at 21: Maintaining Allelic Variation in the Face of Selection
por: Chesler, Elissa J., et al.
Publicado: (2016)

qtl.outbred: Interfacing outbred line cross data with the R/qtl mapping software
por: Nelson, Ronald M, et al.
Publicado: (2011)

Hematopoietic miR155 Deficiency Enhances Atherosclerosis and Decreases Plaque Stability in Hyperlipidemic Mice
por: Donners, Marjo M. P. C., et al.
Publicado: (2012)

Urotensin II Enhances Advanced Aortic Atherosclerosis Formation and Delays Plaque Regression in Hyperlipidemic Rabbits
por: Yu, Qingqing, et al.
Publicado: (2023)

Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe(−/−) mice
por: Sundararaman, Sai Sahana, et al.
Publicado: (2021)

Ablation of CD8α(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice
por: Legein, Bart, et al.
Publicado: (2015)

A diversity outbred F1 mouse model identifies host-intrinsic genetic regulators of response to immune checkpoint inhibitors
por: Hackett, Justin B., et al.
Publicado: (2022)

High-precision genetic mapping of behavioral traits in the diversity outbred mouse population
por: Logan, R W, et al.
Publicado: (2013)

Identification of sample mix-ups and mixtures in microbiome data in Diversity Outbred mice
por: Lobo, Alexandra K, et al.
Publicado: (2021)

Age and diet shape the genetic architecture of body weight in diversity outbred mice
por: Wright, Kevin M, et al.
Publicado: (2022)

Identification of Genetic and Genomic Influences on Progressive Ethanol Consumption in Diversity Outbred Mice
por: Smith, ML, et al.
Publicado: (2023)

Apolipoprotein F concentration, activity, and the properties of LDL controlling ApoF activation in hyperlipidemic plasma
por: Morton, Richard E., et al.
Publicado: (2022)

Which mouse multiparental population is right for your study? The Collaborative Cross inbred strains, their F1 hybrids, or the Diversity Outbred population
por: Keele, Gregory R
Publicado: (2023)

BAFF Receptor mAb Treatment Ameliorates Development and Progression of Atherosclerosis in Hyperlipidemic ApoE(−/−) Mice
por: Kyaw, Tin, et al.
Publicado: (2013)

QTLViewer: an interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations
por: Vincent, Matthew, et al.
Publicado: (2022)

Microbial glutamate metabolism predicts intravenous cocaine self-administration in diversity outbred mice
por: Tran, Thi Dong Binh, et al.
Publicado: (2023)

Identification of Aortic Arch-Specific Quantitative Trait Loci for Atherosclerosis by an Intercross of DBA/2J and 129S6 Apolipoprotein E-Deficient Mice
por: Kayashima, Yukako, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_l538pi2aeesg033shhutodiuvc