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Most synonymous allelic variants in HIV tat are not silent

The genetic code has degenerate codons that produce no change in the translated protein sequence and are generally thought to be silent. However, some synonymous variants are clearly not silent. Herein, we questioned the frequency of non-silent synonymous variants. We tested how random synonymous va...

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Detalles Bibliográficos
Autores principales: Giacoletto, Christopher J., Benjamin, Ronald, Deng, Hong-Wen, Rotter, Jerome I., Schiller, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257815/
https://www.ncbi.nlm.nih.gov/pubmed/36893872
http://dx.doi.org/10.1016/j.ygeno.2023.110603

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