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Crosstalk between diacylglycerol kinase and protein kinase A in the regulation of airway smooth muscle cell proliferation

BACKGROUND: Diacylglycerol kinase (DGK) regulates intracellular signaling and functions by converting diacylglycerol (DAG) into phosphatidic acid. We previously demonstrated that DGK inhibition attenuates airway smooth muscle (ASM) cell proliferation, however, the mechanisms mediating this effect ar...

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Detalles Bibliográficos
Autores principales: Hernandez-Lara, Miguel A., Yadav, Santosh Kumar, Conaway, Stanley, Shah, Sushrut D., Penn, Raymond B., Deshpande, Deepak A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257838/
https://www.ncbi.nlm.nih.gov/pubmed/37301818
http://dx.doi.org/10.1186/s12931-023-02465-8