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SARS-CoV-2-Induced Autoimmune Hepatitis

Few case reports discuss the incidences of autoimmune hepatitis (AIH) in patients after SARS-CoV-2 infection. Here, we present a case of SARS-CoV-2-induced AIH in a male patient who came into the emergency department with complaints of weight loss, poor oral intake, nausea, dark-colored urine, clay-...

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Autores principales: Martini, Nora, Singla, Pranav, Arbuckle, Elizabeth, Goyal, Geetika, Liu, Qiang, Santos-Zabala, Maria L, Zainah, Hanady
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257862/
https://www.ncbi.nlm.nih.gov/pubmed/37309335
http://dx.doi.org/10.7759/cureus.38932
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author Martini, Nora
Singla, Pranav
Arbuckle, Elizabeth
Goyal, Geetika
Liu, Qiang
Santos-Zabala, Maria L
Zainah, Hanady
author_facet Martini, Nora
Singla, Pranav
Arbuckle, Elizabeth
Goyal, Geetika
Liu, Qiang
Santos-Zabala, Maria L
Zainah, Hanady
author_sort Martini, Nora
collection PubMed
description Few case reports discuss the incidences of autoimmune hepatitis (AIH) in patients after SARS-CoV-2 infection. Here, we present a case of SARS-CoV-2-induced AIH in a male patient who came into the emergency department with complaints of weight loss, poor oral intake, nausea, dark-colored urine, clay-colored stools, and scleral icterus, which began two weeks after he tested positive for SARS-CoV-2 PCR. Liver biopsy and subsequent histology confirmed the diagnosis of AIH with the most probable etiology being SARS-CoV-2 infection. The patient was treated with N-acetylcysteine (NAC) and steroids with clinical improvement and eventual discharge home. Our goal is to provide a clinical presentation, treatment, and outcome in a patient with SARS-CoV-2-induced AIH.
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spelling pubmed-102578622023-06-12 SARS-CoV-2-Induced Autoimmune Hepatitis Martini, Nora Singla, Pranav Arbuckle, Elizabeth Goyal, Geetika Liu, Qiang Santos-Zabala, Maria L Zainah, Hanady Cureus Internal Medicine Few case reports discuss the incidences of autoimmune hepatitis (AIH) in patients after SARS-CoV-2 infection. Here, we present a case of SARS-CoV-2-induced AIH in a male patient who came into the emergency department with complaints of weight loss, poor oral intake, nausea, dark-colored urine, clay-colored stools, and scleral icterus, which began two weeks after he tested positive for SARS-CoV-2 PCR. Liver biopsy and subsequent histology confirmed the diagnosis of AIH with the most probable etiology being SARS-CoV-2 infection. The patient was treated with N-acetylcysteine (NAC) and steroids with clinical improvement and eventual discharge home. Our goal is to provide a clinical presentation, treatment, and outcome in a patient with SARS-CoV-2-induced AIH. Cureus 2023-05-12 /pmc/articles/PMC10257862/ /pubmed/37309335 http://dx.doi.org/10.7759/cureus.38932 Text en Copyright © 2023, Martini et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Martini, Nora
Singla, Pranav
Arbuckle, Elizabeth
Goyal, Geetika
Liu, Qiang
Santos-Zabala, Maria L
Zainah, Hanady
SARS-CoV-2-Induced Autoimmune Hepatitis
title SARS-CoV-2-Induced Autoimmune Hepatitis
title_full SARS-CoV-2-Induced Autoimmune Hepatitis
title_fullStr SARS-CoV-2-Induced Autoimmune Hepatitis
title_full_unstemmed SARS-CoV-2-Induced Autoimmune Hepatitis
title_short SARS-CoV-2-Induced Autoimmune Hepatitis
title_sort sars-cov-2-induced autoimmune hepatitis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257862/
https://www.ncbi.nlm.nih.gov/pubmed/37309335
http://dx.doi.org/10.7759/cureus.38932
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