A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach

Anthrax is caused by Bacillus anthracis. Humans are mainly infected through contact with the fur and meat of livestock. The cutaneous form is the most common form. The skin lesions of typical cutaneous anthrax are characterized by shallow ulcers with black crusts, surrounded by small blisters and no...

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Autores principales: Liu, Yushan, Zheng, Gezhi, Li, Jing, Yang, Nan, Li, Juan, Liu, Zhengwen, Han, Qunying, Zhao, Yingren, Du, Fenjing, He, Yingli, Yan, Taotao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257910/
https://www.ncbi.nlm.nih.gov/pubmed/37309378
http://dx.doi.org/10.2147/IDR.S411717
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author Liu, Yushan
Zheng, Gezhi
Li, Jing
Yang, Nan
Li, Juan
Liu, Zhengwen
Han, Qunying
Zhao, Yingren
Du, Fenjing
He, Yingli
Yan, Taotao
author_facet Liu, Yushan
Zheng, Gezhi
Li, Jing
Yang, Nan
Li, Juan
Liu, Zhengwen
Han, Qunying
Zhao, Yingren
Du, Fenjing
He, Yingli
Yan, Taotao
author_sort Liu, Yushan
collection PubMed
description Anthrax is caused by Bacillus anthracis. Humans are mainly infected through contact with the fur and meat of livestock. The cutaneous form is the most common form. The skin lesions of typical cutaneous anthrax are characterized by shallow ulcers with black crusts, surrounded by small blisters and nonpitting edema of nearby tissues. Metagenomic next-generation sequencing (mNGS) is a new pathogenic detection method which is rapid and unbiased. We reported the first case of cutaneous anthrax diagnosed by mNGS. Ultimately, the man received prompt antibiotic therapy and had a good prognosis. In conclusion, mNGS is proved to be a good method for etiological diagnosis, especially for rare infectious diseases.
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spelling pubmed-102579102023-06-12 A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach Liu, Yushan Zheng, Gezhi Li, Jing Yang, Nan Li, Juan Liu, Zhengwen Han, Qunying Zhao, Yingren Du, Fenjing He, Yingli Yan, Taotao Infect Drug Resist Case Report Anthrax is caused by Bacillus anthracis. Humans are mainly infected through contact with the fur and meat of livestock. The cutaneous form is the most common form. The skin lesions of typical cutaneous anthrax are characterized by shallow ulcers with black crusts, surrounded by small blisters and nonpitting edema of nearby tissues. Metagenomic next-generation sequencing (mNGS) is a new pathogenic detection method which is rapid and unbiased. We reported the first case of cutaneous anthrax diagnosed by mNGS. Ultimately, the man received prompt antibiotic therapy and had a good prognosis. In conclusion, mNGS is proved to be a good method for etiological diagnosis, especially for rare infectious diseases. Dove 2023-06-07 /pmc/articles/PMC10257910/ /pubmed/37309378 http://dx.doi.org/10.2147/IDR.S411717 Text en © 2023 Liu et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Report
Liu, Yushan
Zheng, Gezhi
Li, Jing
Yang, Nan
Li, Juan
Liu, Zhengwen
Han, Qunying
Zhao, Yingren
Du, Fenjing
He, Yingli
Yan, Taotao
A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach
title A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach
title_full A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach
title_fullStr A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach
title_full_unstemmed A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach
title_short A Case Report of Cutaneous Anthrax Diagnosed by Using a Metagenomic Next-Generation Sequencing (mNGS) Approach
title_sort case report of cutaneous anthrax diagnosed by using a metagenomic next-generation sequencing (mngs) approach
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10257910/
https://www.ncbi.nlm.nih.gov/pubmed/37309378
http://dx.doi.org/10.2147/IDR.S411717
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